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儿童和青少年髋关节骨样骨瘤。

Osteoid Osteoma About the Hip in Children and Adolescents.

机构信息

Departments of Orthopedic Surgery (C.J.M., M.E.A., Y.J.K., Y.-M.Y., M.B.M., and B.E.H.) and Radiology (S.D.B.), Harvard Medical School and Boston Children's Hospital, Boston, Massachusetts.

出版信息

J Bone Joint Surg Am. 2019 Mar 20;101(6):486-493. doi: 10.2106/JBJS.18.00888.

Abstract

BACKGROUND

The etiology of hip pain in pediatric and adolescent patients can be unclear. Osteoid osteoma (OO) about the hip in children has only been described in case reports or small studies. The present study assessed the clinical presentation and diagnostic course, imaging, and treatment approaches in a large cohort of pediatric cases of OO about the hip.

METHODS

Medical record and imaging results were reviewed for all cases of OO identified within or around the hip joint in patients <20 years old between January 1, 2003, and December 31, 2015, at a tertiary-care pediatric center. Demographic, clinical, and radiographic data were analyzed.

RESULTS

Fifty children and adolescents (52% female; mean age, 12.4 years; age range, 3 to 19 years) were identified. Night pain (90%) and symptom relief with nonsteroidal anti-inflammatory drugs (NSAIDs) (88%) were common clinical findings. Sclerosis/cortical thickening was visible in 58% of radiographs, although a radiolucent nidus was visible in only 42%. Diagnostic imaging findings included perilesional edema and a radiolucent nidus on 100% of available magnetic resonance imaging (MRI) and computed tomography (CT) scans, respectively. Initial alternative diagnoses were given in 23 cases (46%), the most common of which was femoroacetabular impingement (FAI). Delay in diagnosis of >6 months occurred in 43% of patients. Three patients underwent operative procedures for other hip diagnoses, but all had persistent postoperative pain until the OO was treated. Of the 41 patients (82%) who ultimately underwent radiofrequency ablation (RFA), 38 (93%) achieved complete post-RFA symptom resolution.

CONCLUSIONS

Initial misdiagnosis, the most common of which was FAI, and delayed correct diagnosis are common in pediatric OO about the hip. Presenting complaints were variable and nonspecific MRI findings were frequent. Night pain and relief with NSAIDs were present in the vast majority of cases. CT scans provided definitive diagnosis in all patients who received them. As increasing numbers of young, active patients are being evaluated for various causes of hip pain, such as FAI, OO should not be overlooked in the differential diagnosis.

LEVEL OF EVIDENCE

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

儿童和青少年髋关节疼痛的病因可能不明确。儿童髋关节骨样骨瘤(OO)仅在病例报告或小研究中有所描述。本研究评估了在一家三级儿童医疗中心中,大量髋关节 OO 患儿的临床表现、诊断过程、影像学和治疗方法。

方法

对 2003 年 1 月 1 日至 2015 年 12 月 31 日期间,在一个关节内或周围诊断为 OO 的所有<20 岁患者的病历和影像学结果进行了回顾。分析了人口统计学、临床和影像学数据。

结果

共发现 50 名儿童和青少年(52%为女性;平均年龄 12.4 岁;年龄范围 3 至 19 岁)。常见的临床发现包括夜间疼痛(90%)和非甾体抗炎药(NSAIDs)缓解症状(88%)。58%的 X 线片可见硬化/皮质增厚,而仅 42%可见透亮核。诊断性影像学表现包括在所有可获得的磁共振成像(MRI)和计算机断层扫描(CT)上分别可见病灶周围水肿和透亮核。在 23 例(46%)中最初给出了其他诊断,最常见的是股骨髋臼撞击症(FAI)。43%的患者存在>6 个月的诊断延迟。3 名患者因其他髋关节诊断而行手术治疗,但所有患者均在接受 OO 治疗前出现持续的术后疼痛。在最终接受射频消融(RFA)的 41 名患者(82%)中,38 名(93%)患者在 RFA 后完全缓解症状。

结论

在儿童髋关节 OO 中,最初的误诊(最常见的是 FAI)和延迟正确诊断很常见。首发症状多种多样,MRI 表现不具特异性。绝大多数患者都有夜间疼痛和 NSAIDs 缓解症状。在所有接受 CT 扫描的患者中,均做出了明确的诊断。随着越来越多的年轻、活跃的患者因各种髋关节疼痛原因(如 FAI)接受评估,在鉴别诊断中不应忽视 OO。

证据等级

治疗学 IV 级。欲了解完整的证据等级说明,请参见作者须知。

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