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上颌骨黏液纤维瘤、当前概念及鉴别诊断

Myxofibroma of the maxilla, current concepts, and differential diagnosis.

作者信息

Cankaya Abdulkadir Burak, Erdem Mehmet Ali, Bilgic Bilge, Firat Deniz

机构信息

Department of Oral Surgery, Faculty of Dentistry, Istanbul University, Istanbul, Turkey.

Department of Pathology, Faculty of Medicine, Istanbul University, Istanbul, Turkey.

出版信息

J Dent Sci. 2017 Dec;12(4):417-420. doi: 10.1016/j.jds.2013.06.001. Epub 2013 Jul 27.

DOI:10.1016/j.jds.2013.06.001
PMID:30895084
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6395292/
Abstract

Odontogenic myxomas represent a small portion of all odontogenic tumors. A myxoma of the bone is a rare lesion that occurs almost exclusively in the jaws. An odontogenic myxoma has a variable clinical and radiological appearance, and it should be considered in the differential diagnosis of radiolucent and mixed radiolucent-radiopaque lesions of both jaws in all age groups. Myxomas consist of an accumulation of mucoid ground substance with little collagen, the amount of which determines whether it is called a myxofibroma. This paper presents the case of a 39-year-old male with a solid whitish red, nonulcerative, nontender expansion of both the buccal and palatal sides of the right upper alveolar bone. Results of a radiological examination revealed a unilocular radiolucency with cortical expansion and displacement of both the right upper second premolar and the first molar. The lesion was totally excised, and the histopathological examination showed a myxofibroma. Healing was uneventful, and there was no recurrence 12 months after surgical excision. Complete removal of the tumor, leaving no remnants attached to the soft tissue or bone, should be considered because of the well-known potential of myxofibromas to recur.

摘要

牙源性黏液瘤占所有牙源性肿瘤的一小部分。骨黏液瘤是一种罕见的病变,几乎仅发生于颌骨。牙源性黏液瘤具有多样的临床和影像学表现,在各年龄组颌骨透光性及透光-不透光混合性病变的鉴别诊断中均应考虑到该疾病。黏液瘤由含少量胶原蛋白的黏液样基质聚集而成,其胶原蛋白含量决定了它是否被称为黏液纤维瘤。本文报告一例39岁男性病例,其右上牙槽骨颊侧和腭侧出现实性白红色、非溃疡性、无压痛的膨隆。影像学检查结果显示为单房透光区,伴有皮质骨膨胀,右上第二前磨牙和第一磨牙移位。病变被完全切除,组织病理学检查显示为黏液纤维瘤。术后愈合顺利,手术切除12个月后无复发。由于黏液纤维瘤具有众所周知的复发可能性,因此应考虑彻底切除肿瘤,不留任何附着于软组织或骨的残余物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfb/6395292/d6a330763747/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfb/6395292/457c13a754ca/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfb/6395292/96f72480748a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfb/6395292/1e024486874d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfb/6395292/d098f0b55d22/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfb/6395292/d6a330763747/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfb/6395292/457c13a754ca/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfb/6395292/96f72480748a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfb/6395292/1e024486874d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfb/6395292/d098f0b55d22/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0cfb/6395292/d6a330763747/gr5.jpg

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本文引用的文献

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Odontogenic myxoma: a clinicopathologic study of 25 cases.牙源性黏液瘤:25例临床病理研究
Arch Pathol Lab Med. 2006 Dec;130(12):1799-806. doi: 10.5858/2006-130-1799-OMACSO.
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Giant myxomas of the maxillofacial skeleton and skull base.颌面骨骼和颅底的巨大黏液瘤
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Indian J Otolaryngol Head Neck Surg. 2022 Oct;74(Suppl 2):1138-1142. doi: 10.1007/s12070-020-02187-z. Epub 2020 Oct 16.
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Odontogenic myxoma of posterior maxilla - A rare case report.上颌骨后部牙源性黏液瘤——1例罕见病例报告
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