Spector-Bagdady Kayte, Lombardo Paul A
Assistant professor in the Department of Obstetrics and Gynecology and is the chief of the Research Ethics Service in the Center for Bioethics and Social Sciences in Medicine at University of Michigan Medical School.
Regents' professor and the Bobby Lee Cook professor of law in the Center for Law, Health and Society at Georgia State University College of Law.
Ethics Hum Res. 2019 Mar;41(2):29-34. doi: 10.1002/eahr.500010.
The U.S. Public Health Service's sexually transmitted disease (STD) experiments in Guatemala are an important case study not only in human subjects research transgressions but also in the response to serious lapses in research ethics. This case study describes how individuals in the STD experiments were tested, exposed to STDs, and exploited as the source of biological specimens-all without informed consent and often with active deceit. It also explores and evaluates governmental and professional responses that followed the public revelation of these experiments, including by academic institutions, professional organizations, and the U.S. federal government, pushing us to reconsider both how we prevent such lapses in the future and how we respond when they are first revealed.
美国公共卫生服务局在危地马拉进行的性传播疾病（STD）实验是一个重要的案例研究，不仅涉及人体受试者研究中的违规行为，还涉及对研究伦理严重失误的应对。本案例研究描述了性传播疾病实验中的个体是如何被检测、接触性传播疾病并被当作生物样本来源加以利用的——所有这些都是在未获得知情同意的情况下进行的，而且常常伴有主动欺骗行为。它还探讨并评估了这些实验公开披露后政府和专业机构的应对措施，包括学术机构、专业组织和美国联邦政府的措施，促使我们重新思考未来如何防止此类失误，以及在失误首次被揭露时如何应对。
