Raś Renata, Barnaś Edyta, Magierło Joanna Skręt-, Drozdzowska Anna, Bartosiewicz Ewelina, Sobolewski Marek, Skręt Andrzej, Gutkowski Krzysztof
Obstetrics and Gynecology Clinic, Clinical Hospital No1 Rzeszow, University of Rzeszow.
Department of Physics, Rzeszow University of Technology.
Medicine (Baltimore). 2019 Mar;98(12):e14929. doi: 10.1097/MD.0000000000014929.
The final diagnosis of ovarian cancer is based on surgery and pathological verification. Therefore patients who are presented to surgery may be described only as supposed ovarian cancer. According to the literature the diagnosis of ovarian cancer is confirmed only in 2/3 of them. The rest are that which mimic ovarian cancer. One of them is colorectal cancer. Colonoscopy is a gold standard in its diagnostics. On the other hand, ovarian cancer may disturb the bowel patency and makes the bowel resection or stoma necessary.The main aim was to find out the distribution of bowel patency disturbances in ovarian cancer patients during preoperative colonoscopy and to assess their predictive value with respect to the bowel resection or stoma and the additional aim to identify the pathologies which mimic the ovarian cancer.In a prospective study among 104 patients with supposed ovarian cancer, primary ovarian cancer was diagnosed in 68 patients. The rest of them suffered from colorectal cancer found at colonoscopy (N = 6), ovarian benign pathology (N = 8), ovarian borderline tumor (N = 5), and other nonandexal malignant diseases (N = 17). In ovarian cancer group dominated serous carcinoma and fedération international de gynécologie et d'obstétrique stage 3 (N = 33).During preoperative colonoscopy in ovarian cancer patients, the complete obstruction was found in 27.9%, and relative risk of bowel resection or stoma was in them 4.29 and 4.38, respectively. Another colonoscopic finding was limited patency caused by extrinsic compression (29%) which is connected with relative risk of bowel resection or stoma 3.16 and 3.21 accordingly. The last colonoscopy finding was described as moderate limited patency of unknown origin (20.6%) and the relative risk of bowel resection or stoma was 5.14 and 4.17, respectively.Colonoscopy enables the diagnoses of colorectal cancer one of the diseases which mimic ovarian cancer in patients supposed to have this diseases.Bowel patency disturbances found at colonoscopy are a potential risk factor to intestine resection or ostomy.Colonoscopy is not fully noninvasive procedure and its obligatory use in patients supposed to have ovarian cancer should be limited to the cases with specific symptoms, and tumor marker pattern. Preoperative computed tomography, dedicated to bowel examination, candidates as an alternative to colonoscopy, but not completely.
卵巢癌的最终诊断基于手术和病理验证。因此，接受手术的患者可能仅被描述为疑似卵巢癌。根据文献，只有三分之二的疑似患者最终被确诊为卵巢癌。其余的则是疑似卵巢癌但实际为其他疾病的患者，其中之一是结直肠癌。结肠镜检查是其诊断的金标准。另一方面，卵巢癌可能会干扰肠道通畅，导致肠道切除或造口术成为必要。主要目的是找出卵巢癌患者术前结肠镜检查中肠道通畅障碍的分布情况，并评估其对肠道切除或造口术的预测价值，另外一个目的是识别出疑似卵巢癌的其他疾病。在一项针对104例疑似卵巢癌患者的前瞻性研究中，68例被诊断为原发性卵巢癌。其余患者患有结肠镜检查发现的结直肠癌（6例）、卵巢良性病变（8例）、卵巢交界性肿瘤（5例）以及其他非附件恶性疾病（17例）。卵巢癌组中浆液性癌和国际妇产科联合会（FIGO）3期占主导（33例）。在卵巢癌患者的术前结肠镜检查中，发现完全性梗阻的占27.9%，其肠道切除或造口的相对风险分别为4.29和4.38。另一个结肠镜检查结果是由外部压迫导致的有限通畅（29%），相应的肠道切除或造口的相对风险为3.16和3.21。最后一个结肠镜检查结果被描述为原因不明的中度有限通畅（20.6%），肠道切除或造口的相对风险分别为5.14和4.17。结肠镜检查能够诊断出结直肠癌，这是疑似卵巢癌患者中会误诊为卵巢癌的疾病之一。结肠镜检查发现的肠道通畅障碍是肠道切除或造口的潜在危险因素。结肠镜检查并非完全无创的检查方法，对于疑似卵巢癌患者，其强制使用应仅限于有特定症状和肿瘤标志物模式的病例。专门用于肠道检查的术前计算机断层扫描可作为结肠镜检查的替代方法，但并不完全能替代。
Zotero 插件
