双环丙叉基-银（I）配合物催化苄醇的选择性有氧氧化

Selective Aerobic Oxidation of Benzylic Alcohols Catalyzed by a Dicyclopropenylidene-Ag(I) Complex.

作者信息

Mir Roya, Rowshanpour Rozhin, Dempsey Katie, Pilkington Melanie, Dudding Travis

机构信息

Department of Chemistry , Brock University , 1812 Sir Isaac Brock Way , St. Catharines , Ontario , Canada L2S 3A1.

出版信息

J Org Chem. 2019 May 3;84(9):5726-5731. doi: 10.1021/acs.joc.9b00624. Epub 2019 Apr 1.

DOI:10.1021/acs.joc.9b00624

PMID:30896944

Abstract

The unprecedented synthesis, single-crystal X-ray structure, and first catalytic application of a dicarbene-Ag(I) complex [Ag(BAC)][COCF] (BAC = bis(diisopropyl)aminocyclopropenylidene) is reported. This novel complex provides a versatile catalytic platform for selective aerobic oxidation of benzylic alcohols to aldehyde or ketone products in high yields. Ease of experimental execution coupled with the use of abundant atmospheric molecular oxygen as an oxidant and low catalyst loading are inherit strengths of these oxidations.

摘要

报道了二卡宾-Ag(I)配合物[Ag(BAC)][COCF]（BAC = 双（二异丙基）氨基环丙烯叉）的前所未有的合成、单晶X射线结构及首次催化应用。这种新型配合物为苄醇选择性好氧氧化为醛或酮产物提供了一个通用的催化平台，产率很高。易于实验操作，加上使用丰富的大气分子氧作为氧化剂以及低催化剂负载量，是这些氧化反应的固有优势。