Chemistry Department, Faculty of Science, University of Kuwait, P.O. Box 5969, Safat 13060, Kuwait.
Department of Chemistry, Faculty of Science, Cairo University, Giza 12613, Egypt.
Molecules. 2019 Mar 20;24(6):1110. doi: 10.3390/molecules24061110.
Reactions of a series of 3-oxo-2-arylhydrazonopropanal derivatives with two molar ratio of ammonium acetate afforded a library of tetrasubstituted 2,3,6,7,9-pentaazabicyclo[3.3.1]nona- 3,7-diene derivatives in good to excellent isolated yields. The reaction was activated with triethylamine catalyst under three different heating modes: thermal, ultrasonic and microwave irradiating conditions in ethanol solvent. The structures of the isolated products were fully characterized by spectral and analytical data as well as X-ray single crystal of selected examples.
一系列 3-氧代-2-芳基腙丙醛衍生物与两倍摩尔比的醋酸铵反应,以良好至优秀的分离产率得到了一系列四取代的 2,3,6,7,9-五氮杂双环[3.3.1]壬-3,7-二烯衍生物库。反应在三乙胺催化剂的作用下,在三种不同的加热模式下激活:热、超声和微波辐射条件下在乙醇溶剂中进行。通过光谱和分析数据以及对选定实例的 X 射线单晶结构对分离产物的结构进行了充分的表征。