Abidjan Heart Institute, 01 BP V206 Abidjan, Côte d'Ivoire.
Abidjan Heart Institute, 01 BP V206 Abidjan, Côte d'Ivoire.
Arch Cardiovasc Dis. 2019 May;112(5):296-304. doi: 10.1016/j.acvd.2019.01.003. Epub 2019 Mar 18.
Coronary angiography data are scarce for black patients with diabetes.
To assess coronary angiography findings in patients with diabetes at the Abidjan Heart Institute.
This observational cross-sectional survey was conducted between 1 April 2010 and 31 December 2014. All patients admitted for known or suspected coronary artery disease who underwent coronary angiography were included in the Registre Prospectif des Actes de Cardiologie Interventionnelle de l'Institut de Cardiologie d'Abidjan. We analysed and compared coronary angiographical findings in patients with and without diabetes.
Eighty patients with diabetes were compared with 353 patients without diabetes. Patients with diabetes were significantly older (58.7±8.9 vs 52.1±11.5 years; P<0.001). Hypertension and hypertriglyceridaemia were significantly associated with diabetes (P<0.001 and P=0.04, respectively). A higher proportion of patients with diabetes had an abnormal coronary angiogram (85.0% vs 67.7%; P=0.002). Coronary artery disease in patients with diabetes was predominantly characterized by multivessel disease (P<0.001). Cardiovascular risk factors associated with diabetes influenced the severity of coronary lesions. A SYNTAX score≥33 was found in a higher proportion of patients with diabetes (12.5% vs 7.1%). In the multivariable logistic regression, after adjustment, age>60 years (hazard ratio 2.53, 95% confidence interval 1.59-4.04; P<0.001) and diabetes (hazard ratio 2.12, 95% confidence interval 1.26-3.57; P=0.004) were associated with multivessel coronary artery disease.
In our study, diabetes emerged as a risk factor for multivessel coronary artery disease. Future studies should help to define the long-term prognosis of these patients, and to assess the benefits of myocardial revascularization procedures.
关于患有糖尿病的黑人患者的冠状动脉造影数据十分有限。
评估阿比让心脏研究所中患有糖尿病的患者的冠状动脉造影结果。
这是一项于 2010 年 4 月 1 日至 2014 年 12 月 31 日进行的观察性横断面研究。所有因已知或疑似冠状动脉疾病入院并接受冠状动脉造影的患者均被纳入 Registre Prospectif des Actes de Cardiologie Interventionnelle de l'Institut de Cardiologie d'Abidjan。我们分析并比较了有糖尿病和无糖尿病患者的冠状动脉造影结果。
80 例糖尿病患者与 353 例无糖尿病患者进行了比较。糖尿病患者的年龄明显更大（58.7±8.9 岁 vs 52.1±11.5 岁；P<0.001）。高血压和高三酰甘油血症与糖尿病显著相关（P<0.001 和 P=0.04）。糖尿病患者中异常冠状动脉造影的比例更高（85.0% vs 67.7%；P=0.002）。糖尿病患者的冠状动脉疾病主要表现为多血管疾病（P<0.001）。与糖尿病相关的心血管危险因素影响了冠状动脉病变的严重程度。糖尿病患者的 SYNTAX 评分≥33 的比例更高（12.5% vs 7.1%）。在多变量逻辑回归中，经调整后，年龄>60 岁（危险比 2.53，95%置信区间 1.59-4.04；P<0.001）和糖尿病（危险比 2.12，95%置信区间 1.26-3.57；P=0.004）与多血管冠状动脉疾病相关。
在我们的研究中，糖尿病成为多血管冠状动脉疾病的一个危险因素。未来的研究应该有助于确定这些患者的长期预后，并评估心肌血运重建术的益处。
