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勃起功能障碍的缺血性阴茎异常勃起的系统评价:我们需要更多的数据吗?

A Systematic Review on Ischemic Priapism and Immediate Implantation: Do We Need More Data?

机构信息

Department of Urology, University of Naples Federico II, Naples, Italy.

Department of Urology, University of Naples Federico II, Naples, Italy.

出版信息

Sex Med Rev. 2019 Jul;7(3):530-534. doi: 10.1016/j.sxmr.2018.10.007. Epub 2019 Mar 19.

Abstract

INTRODUCTION

Ischemic priapism (IP) is the most common form of priapism. In cases of priapism persisting for >36 hours, conservative management usually fails, and the patients' erectile tissue will be inevitably compromised, resulting in corporal fibrosis, shortening of the penis, and refractory erectile dysfunction. In this subset of patients, early implantation of a penile prosthesis (PP) could be a solution for both the priapic episode and the erectile dysfunction.

AIM

To analyze the current literature with regard to the correlation between refractory ischemic priapism and immediate implantation of PP.

METHODS

An extensive literature research was conducted to retrieve studies focusing on immediate PP implantation in patients suffering from refractory ischemic priapism (RIP).

MAIN OUTCOME MEASURES

We evaluated the functional outcomes of patients who have undergone the immediate insertion of a PP as treatment for an acute episode of IP refractory to medical therapy or shunt surgery.

RESULTS

Nine studies were included in this systematic review, including 3 case reports and 6 retrospective analyses. All studies agreed that in patients with RIP, early insertion of a PP is a safe and effective procedure, and all studies but 1 preferred malleable implants to inflatable implants.

CONCLUSION

The systematic review does not demonstrate superiority of immediatePP implantation over delayed PP implantation, because none of the studies was designed with this purpose. However, considering the reduced complication rate and the ease of the procedure, all studies are in favor of early implantation over delayed implantation. Capece M, La Rocca R, Mirone V, et al. A Systematic Review on Ischemic Priapism and Immediate Implantation: Do We Need More Data? Sex Med Rev 2018;7:530-534.

摘要

引言

缺血性阴茎异常勃起(IP)是最常见的异常勃起形式。对于持续>36 小时的异常勃起,保守治疗通常无效,患者的勃起组织将不可避免地受损,导致 corporal 纤维化、阴茎缩短和难治性勃起功能障碍。在这部分患者中,早期植入阴茎假体(PP)可能是解决异常勃起发作和勃起功能障碍的一种方法。

目的

分析目前关于难治性缺血性异常勃起与即刻植入 PP 之间相关性的文献。

方法

进行了广泛的文献研究,以检索专注于难治性缺血性异常勃起(RIP)患者即刻植入 PP 的研究。

主要观察指标

我们评估了接受即刻插入 PP 治疗难治性缺血性异常勃起急性发作的患者的功能结局,这些患者对药物治疗或分流手术无反应。

结果

本系统评价纳入了 9 项研究,包括 3 例病例报告和 6 项回顾性分析。所有研究均认为,对于 RIP 患者,早期植入 PP 是一种安全有效的方法,除 1 项研究外,所有研究均倾向于使用可弯曲植入物而不是可充气植入物。

结论

系统评价并未证明即刻植入 PP 优于延迟植入 PP,因为没有一项研究是为此目的而设计的。然而,考虑到较低的并发症发生率和手术的简易性,所有研究都倾向于早期植入而不是延迟植入。Capece M、La Rocca R、Mirone V 等人。《缺血性阴茎异常勃起与即刻植入:我们是否需要更多数据?》《性医学评论》2018 年;7:530-534。

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