铑（III）作为X射线对细胞作用的增效剂。

Rhodium(III) as a potentiator of the effects of X-rays on cells.

作者信息

Richmond R C, Centilli M A, Cross M H, Powers E L

出版信息

Int J Radiat Biol Relat Stud Phys Chem Med. 1986 Aug;50(2):337-43. doi: 10.1080/09553008614550711.

Abstract

A rhodium compound, Rh(NH3)3Cl3, does not sensitize the spores of Bacillus megaterium to X-rays. However, it is a very effective sensitizer of vegetative cells of Staphylococcus aureus, raising the sensitivity four times in O2 and over 100 times in anoxia. The inhibition by oxygen of the sensitizing action of Rh(III), which operates over a wide range of [O2], is noteworthy. These experiments were performed in saline-phosphate buffer using 50 kVp X-rays. The results are discussed in terms of the known radiation chemistry of this compound.

摘要

铑化合物Rh(NH3)3Cl3不会使巨大芽孢杆菌的孢子对X射线敏感。然而，它是金黄色葡萄球菌营养细胞非常有效的敏化剂，在有氧条件下将敏感性提高四倍，在无氧条件下提高100倍以上。值得注意的是，在很宽的[O2]范围内起作用的氧气对Rh(III)敏化作用的抑制。这些实验是在磷酸盐缓冲盐溶液中使用50 kVp的X射线进行的。根据该化合物已知的辐射化学对结果进行了讨论。