D'Agostino Erin, Calnan Daniel R, Hickey William, Bauer David F
1Geisel School of Medicine, Dartmouth College, Hanover; and.
2Section of Neurosurgery, Department of Surgery, Dartmouth-Hitchcock Medical Center, and.
J Neurosurg Pediatr. 2019 Mar 22;23(6):732-736. doi: 10.3171/2019.1.PEDS18372. Print 2019 Jun 1.
Intracranial collision tumors have rarely been reported in the literature and generally include at least 1 malignant tumor component. Subependymoma with dysembryoplastic neuroepithelial tumor (DNET) is an as-yet unreported combination. Both components are uncommon tumors, and presentation in the foramen of Monro is even more unusual. A 16-year-old male patient with a past medical history significant for asthma presented with a 3-month history of headaches and radiographic evidence of mild obstructive hydrocephalus secondary to a nonenhancing ventricular lesion at the foramen of Monro. He underwent endoscopic biopsy and resection. Pathological analysis revealed distinct components of subependymoma and DNET. At the 1-year follow-up, the patient was doing well without regrowth of tumor. The authors describe a case of intracranial collision tumor demonstrating 2 grade I components: a novel combination of subependymoma and DNET.
颅内碰撞瘤在文献中鲜有报道,通常至少包含1个恶性肿瘤成分。室管膜下瘤合并胚胎发育不良性神经上皮肿瘤(DNET)是一种尚未见报道的组合。这两种成分均为罕见肿瘤,而在孟氏孔出现则更为罕见。一名有哮喘病史的16岁男性患者,出现头痛3个月,影像学检查显示孟氏孔处有一不强化的脑室病变,继发轻度梗阻性脑积水。他接受了内镜活检和切除术。病理分析显示室管膜下瘤和DNET的不同成分。在1年的随访中,患者情况良好,肿瘤未复发。作者描述了一例颅内碰撞瘤,其显示出2个I级成分:室管膜下瘤和DNET的一种新组合。