Yamamoto Hiroshi, Kadohama Takayuki, Yamaura Gembu, Tanaka Fuminobu, Takagi Daichi, Kiryu Kentaro, Itagaki Yoshinori
Department of Cardiovascular Surgery, Akita University Graduate School of Medicine, Akita, Japan.
Department of Cardiovascular Surgery, Akita University Graduate School of Medicine, Akita, Japan.
J Thorac Cardiovasc Surg. 2020 Jan;159(1):36-45. doi: 10.1016/j.jtcvs.2019.01.125. Epub 2019 Feb 15.
The aim of this study was to investigate the effect of frozen elephant trunk deployment from the zone 0 aorta to the descending aorta on early and midterm postoperative results in patients with acute type A aortic dissection.
Between October 2014 and April 2018, 108 patients underwent a combined strategy of frozen elephant trunk deployment, ascending aortic replacement, and arch vessel reconstruction ("zone 0 arch repair" strategy) for acute type A aortic dissection (excluding DeBakey type II). Of the 108 patients, 32 (29.6%) had primary tears of the aortic arch or descending aorta.
The 30-day mortality rate was 2.8% (3 patients), and in-hospital mortality rate was 6.5% (7 patients). New-onset permanent neurologic dysfunction and spinal cord injury occurred in 3.7% and 0% of patients, respectively. Five of the 101 survivors underwent thoracic endovascular aortic repair during hospitalization (2 for rapid false lumen enlargement; 3 for true lumen stenosis). The overall survival was 89.8%, 88.1%, and 88.1% at 1, 2, and 3 years, respectively. The cumulative incidence of distal aortic reintervention was 5.8%, 9.1%, and 9.1% at 1, 2, and 3 years, respectively. Two patients underwent thoracic endovascular aortic repair for distal aortic enlargement after discharge.
The use of the "zone 0 arch repair" strategy can eliminate the need for invasive aortic arch resection. It also eliminates the false lumen and produces satisfactory early and midterm postoperative results. Therefore, it can be an alternative to hemiarch and total arch replacements, which are based on a conventional "tear-oriented resection" strategy.
本研究旨在探讨从0区主动脉至降主动脉植入带膜支架象鼻术对急性A型主动脉夹层患者术后早期和中期结果的影响。
2014年10月至2018年4月,108例急性A型主动脉夹层(不包括DeBakey II型)患者接受了带膜支架象鼻术、升主动脉置换及弓部血管重建的联合策略(“0区弓部修复”策略)。108例患者中,32例(29.6%)主动脉弓或降主动脉存在原发性破口。
30天死亡率为2.8%(3例患者),住院死亡率为6.5%(7例患者)。新发永久性神经功能障碍和脊髓损伤的发生率分别为3.7%和0%。101例幸存者中有5例在住院期间接受了胸主动脉腔内修复术(2例因假腔迅速扩大;3例因真腔狭窄)。1年、2年和3年的总生存率分别为89.8%、88.1%和88.1%。1年、2年和3年远端主动脉再次干预的累积发生率分别为5.8%、9.1%和9.1%。2例患者出院后因远端主动脉扩张接受了胸主动脉腔内修复术。
“0区弓部修复”策略的应用可避免进行侵入性主动脉弓切除术。该策略还可消除假腔,并产生令人满意的术后早期和中期结果。因此,它可作为基于传统“撕裂导向切除术”策略的半弓和全弓置换术的替代方案。