Sundaram Kavin, Warren Jared, Anis Hiba, George Jaiben, Murray Trevor, Higuera Carlos A, Piuzzi Nicolas S
Department of Orthopaedic Surgery, Cleveland Clinic, 9500 Euclid Ave/A41, Cleveland, OH 44195, United States of America.
All-Indian Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.
Knee. 2019 Jun;26(3):720-728. doi: 10.1016/j.knee.2019.02.009. Epub 2019 Mar 20.
The association of postoperative complications and obesity after total knee arthroplasty (TKA) has been well described. However, the effect of an increased body-mass index (BMI) on postoperative complications after unicompartmental knee arthroplasty (UKA) is controversial. Therefore, our aim was to assess the influence of BMI on 30-day postoperative complications after UKA when analyzed as both a categorical and continuous variable.
The American College of Surgeons National Quality Improvement Program (NSQIP) database was used to identify a total of 8029 patients who underwent UKA from January 1, 2008, to December 31, 2016. The database was queried for over 30 unique complications occurring within 30 days. The impact of BMI on short-term outcomes was assessed as a categorical variable using univariate and multivariate regression. Additionally, BMI was assessed as a continuous variable using spline regressions.
Univariate regression analysis revealed that compared to normal weight patients, overweight patients had a lower risk of major complication (odds ratio [OR], 0.506; 95% confidence interval [CI], 0.279-0.918; p = 0.025), and any complication ([OR] 0.632; 95% CI, 0.423-0.944; p = 0.025) Multivariate regression analysis found no statistically significant relationship between categorical BMI and complications or outcomes, except for morbidly obese patients who had a greater risk of superficial SSI (p = 0.026). Spline regression found no statistically significant non-linear relationships between BMI and any complication (p = 0.4687), major complications (p = 0.1567), or minor complications (p = 0.4071).
Overweight and obese individuals who undergo UKA may not have an increased risk of 30-day postoperative complications compared to normal weight individuals.
全膝关节置换术(TKA)后术后并发症与肥胖之间的关联已得到充分描述。然而,体重指数(BMI)升高对单髁膝关节置换术(UKA)后术后并发症的影响存在争议。因此,我们的目的是在将BMI作为分类变量和连续变量进行分析时,评估其对UKA术后30天并发症的影响。
利用美国外科医师学会国家质量改进计划(NSQIP)数据库,确定2008年1月1日至2016年12月31日期间共8029例行UKA的患者。查询该数据库中30天内发生的30多种独特并发症。使用单变量和多变量回归将BMI作为分类变量评估其对短期结局的影响。此外,使用样条回归将BMI作为连续变量进行评估。
单变量回归分析显示,与正常体重患者相比,超重患者发生重大并发症的风险较低(优势比[OR],0.506;95%置信区间[CI],0.279 - 0.918;p = 0.025),发生任何并发症的风险也较低([OR] 0.632;95% CI,0.423 - 0.944;p = 0.025)。多变量回归分析发现,除病态肥胖患者发生浅表手术部位感染的风险较高外(p = 0.026),分类BMI与并发症或结局之间无统计学显著关系。样条回归发现BMI与任何并发症(p = 0.4687)、重大并发症(p = 0.1567)或轻微并发症(p = 0.4071)之间无统计学显著的非线性关系。
与正常体重个体相比,接受UKA的超重和肥胖个体术后30天并发症风险可能并未增加。