From the Veterans Affairs Greater Los Angeles Parkinson's Disease Research, Education and Clinical Center (K.I.C., L.K.E., M.G.M.); University of California Los Angeles David Geffen School of Medicine (K.I.C., E.M.C., F.B.); Siebens Patient Care Communications LLC (H.C.S.), Seal Beach; Veterans Affairs Sepulveda Ambulatory Care Center (M.L.L.), North Hills; University of California Los Angeles Fielding School of Public Health (M.L.L.); Veterans Affairs Geriatric Research, Education and Clinical Center and Center for the Study of Healthcare Innovation, Implementation and Policy (D.A.G.), Los Angeles; Kaiser Permanente Research (B.S.M.), Pasadena; University of California San Francisco (M.K.C.); and Icahn School of Medicine at Mount Sinai (B.G.V.), New York, NY.
Neurology. 2019 Apr 16;92(16):e1831-e1842. doi: 10.1212/WNL.0000000000007324. Epub 2019 Mar 22.
To test effects on care quality of Chronic Care Model-based Parkinson disease (PD) management.
This 2-group stratified randomized trial involved 328 veterans with PD in southwestern United States. Guided care management, led by PD nurses, was compared to usual care. Primary outcomes were adherence to 18 PD care quality indicators. Secondary outcomes were patient-centered outcome measures. Data sources were telephone survey and electronic medical record (EMR). Outcomes were analyzed as intent-to-treat comparing initial and final survey and repeated-measures mixed-effects models.
Average age was 71 years; 97% of participants were male. Mean proportion of participants receiving recommended PD care indicators was significantly higher for the intervention than for usual care (0.77 vs 0.58) (mean difference 0.19, 95% confidence interval [CI] 0.16, 0.22). Of 8 secondary outcomes, the only significant difference of the changes over time was in the positive Patient Health Questionnaire-2 depression screen for intervention minus usual care (-11.52 [95% CI -20.42, -2.62]).
A nurse-led chronic care management intervention, Care Coordination for Health Promotion and Activities in Parkinson's Disease (CHAPS), substantially increased adherence to PD quality of care indicators among veterans with PD, as documented in the EMR. Of 8 secondary outcomes assessed, a screening measure for depressive symptomatology was the only measure that was better in the intervention compared to usual care. More telephone calls in CHAPS were the only utilization difference over usual care. While CHAPS appears promising for improving PD care, additional iterative research is needed to refine the CHAPS model in routine clinical care so that it measurably improves patient-centered outcomes (NCT01532986).
This study provides Class I evidence that for patients with PD, CHAPS increased adherence to PD quality of care indicators.
测试基于慢性病护理模式的帕金森病(PD)管理对护理质量的影响。
这是一项在美国西南部进行的、2 组分层随机试验,共纳入 328 名 PD 退伍军人。由 PD 护士主导的指导性护理管理与常规护理进行比较。主要结局是 PD 护理质量指标的依从性。次要结局是患者为中心的结局指标。数据来源为电话调查和电子病历(EMR)。采用意向治疗分析方法比较初始和最终调查结果,并采用重复测量混合效应模型进行分析。
平均年龄为 71 岁,97%的参与者为男性。干预组接受推荐 PD 护理指标的比例明显高于常规护理组(0.77 比 0.58)(平均差异 0.19,95%置信区间[CI]0.16,0.22)。在 8 项次要结局中,干预组与常规护理组之间唯一具有统计学意义的时间变化差异是干预组减去常规护理组的患者健康问卷-2 抑郁筛查阳性率(-11.52[95%CI-20.42,-2.62])。
以护士为基础的慢性病护理管理干预措施,即帕金森病健康促进和活动协调护理(CHAPS),在记录于 EMR 的退伍军人 PD 患者中,显著提高了 PD 护理质量指标的依从性。在评估的 8 项次要结局中,干预组与常规护理组相比,唯一更好的测量方法是抑郁症状筛查测量。CHAPS 组与常规护理组唯一的利用差异是 CHAPS 组的电话随访次数更多。虽然 CHAPS 似乎有望改善 PD 护理,但需要进一步的迭代研究来完善 CHAPS 模型,以便在常规临床护理中可测量地改善以患者为中心的结局(NCT01532986)。
本研究提供了 I 级证据,表明对于 PD 患者,CHAPS 提高了 PD 护理质量指标的依从性。