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Children with severe persistent asthma have disparate peripheral blood and lower airway eosinophil levels.

作者信息

Ribeiro Victoria, Andrade Jade, Rose Samantha, Spencer Chantal, Vicencio Alfin, Bunyavanich Supinda

机构信息

Division of Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY; Department of Genetic and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY.

Division of Pulmonology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY.

出版信息

J Allergy Clin Immunol Pract. 2019 Sep-Oct;7(7):2494-2496. doi: 10.1016/j.jaip.2019.03.009. Epub 2019 Mar 21.

DOI:10.1016/j.jaip.2019.03.009
PMID:30904479
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6733616/
Abstract
摘要

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本文引用的文献

1
Leveraging -omics for asthma endotyping.利用组学进行哮喘表型分型。
J Allergy Clin Immunol. 2019 Jul;144(1):13-23. doi: 10.1016/j.jaci.2019.05.015.
2
The Role of Neutrophils in Asthma.中性粒细胞在哮喘中的作用。
Immunol Allergy Clin North Am. 2018 Nov;38(4):629-638. doi: 10.1016/j.iac.2018.06.005. Epub 2018 Sep 18.
3
Biomarkers for severe eosinophilic asthma.严重嗜酸性粒细胞性哮喘的生物标志物。
J Allergy Clin Immunol. 2017 Dec;140(6):1509-1518. doi: 10.1016/j.jaci.2017.10.005.
4
Biologics and biomarkers for asthma, urticaria, and nasal polyposis.哮喘、荨麻疹和鼻息肉的生物制剂和生物标志物。
J Allergy Clin Immunol. 2017 May;139(5):1411-1421. doi: 10.1016/j.jaci.2017.03.006.
5
Interleukin-5 Antagonists Usher in a New Generation of Asthma Therapy.白细胞介素-5拮抗剂引领新一代哮喘治疗。
Curr Allergy Asthma Rep. 2016 Nov;16(11):80. doi: 10.1007/s11882-016-0662-1.
6
Severe asthma in children.儿童重度哮喘
J Allergy Clin Immunol Pract. 2014 Sep-Oct;2(5):489-500. doi: 10.1016/j.jaip.2014.06.022.
7
Blood eosinophil counts rarely reflect airway eosinophilia in children with severe asthma.血液嗜酸性粒细胞计数很少反映严重哮喘儿童的气道嗜酸性粒细胞增多。
Allergy. 2013 Mar;68(3):402-6. doi: 10.1111/all.12101. Epub 2013 Jan 25.
8
Mepolizumab for prednisone-dependent asthma with sputum eosinophilia.美泊利单抗用于治疗伴有痰液嗜酸性粒细胞增多的泼尼松依赖型哮喘。
N Engl J Med. 2009 Mar 5;360(10):985-93. doi: 10.1056/NEJMoa0805435.