National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
Ethn Dis. 2019 Feb 21;29(Suppl 1):65-70. doi: 10.18865/ed.29.S1.65. eCollection 2019.
Critical to eliminating the sex and gender gap in cardiovascular health is addressing known differences in disease burden, disparities in treatment and clinical outcomes, and the scientific importance of sex as a biological variable that influences resilience, pathophysiology, and ultimately the health of women. Furthermore, key disparities exist at the intersection of sex/gender and race/ethnicity where women of color are disproportionately affected by higher burden of disease and poorer outcomes in several cardiovascular conditions. Through efforts to galvanize strategic partnerships, sets forth research priorities across all of its objectives relevant to the cardiovascular health of women; it encourages strategic partnerships in both establishing and implementing research priorities. The Vision promotes a promise of precision medicine that embraces sex as its highest order, leverages an integrated approach to data science, explores sex influences on molecular underpinnings of disease, and advances sex-specific and race-sex interaction analyses toward the elimination of gaps in the cardiovascular care and health of all women.
消除心血管健康领域中的性别差距的关键是解决已知的疾病负担差异、治疗和临床结果差异，以及性别作为影响韧性、病理生理学、最终影响女性健康的生物学变量的重要性。此外，在性别/性别和种族/族裔的交叉点存在关键差异，有色人种的女性在几种心血管疾病中受到更高疾病负担和较差结果的不成比例影响。通过努力激发战略伙伴关系，该计划在与女性心血管健康相关的所有目标中制定了研究重点；它鼓励在制定和实施研究重点方面建立战略伙伴关系。该愿景促进了精准医学的承诺，将性别作为其最高秩序，利用数据科学的综合方法，探索性别对疾病分子基础的影响，并推进性别特异性和种族性别相互作用分析，以消除所有女性心血管护理和健康方面的差距。
