Bergmann P, Franz H
Acta Histochem Suppl. 1986;33:9-16.
The actual definitions of lectins are presented and discussed and lectins are classified as one group of the affinitins. The ability of lectins to bind carbohydrates serves as a widely used principle in the nature for cell recognition and adhesion processes. By means of labelled glycoconjugates the identification, localization and quantitation of receptor bound lectins can be investigated as by lectinological as by a combination of lectinological and immunological reactions. The special properties of toxic lectins are discussed by use of the lectin I from mistletoe as characteristic example. The coupling of A-chains with antibodies (immunotoxins) or other haptomers (affinotoxins) leads to agents render it possible to influence directly cell functions.
本文介绍并讨论了凝集素的实际定义，并将凝集素归类为亲和素的一个类别。凝集素与碳水化合物结合的能力是自然界中细胞识别和黏附过程广泛应用的原理。通过标记糖缀合物，可利用凝集素学方法或凝集素学与免疫反应相结合的方法研究受体结合凝集素的鉴定、定位和定量。以槲寄生凝集素I为例讨论了有毒凝集素的特殊性质。A链与抗体（免疫毒素）或其他半抗原（亲和毒素）偶联可产生能直接影响细胞功能的制剂。
