玻璃体腔注射贝伐单抗治疗侵袭性早产儿视网膜病变后发生双侧完全性白内障
Bilateral Total Cataract After Intravitreal Bevacizumab Injection in Aggressive Posterior Retinopathy of Prematurity.
作者信息
Khokhar Sudarshan, Chandra Parijat, Gupta Yogita, Kumawat Devesh, Dhull Chirakshi
出版信息
J Pediatr Ophthalmol Strabismus. 2019 Mar 25;56:e28-e30. doi: 10.3928/01913913-20190219-02.
PMID:30907975
Abstract
The authors report a rare occurrence of bilateral cataract in eyes with aggressive posterior retinopathy of prematurity after bilateral administration of intravitreal bevacizumab in a neonate, with no evidence of lens touch. Although the exact mechanism of cataractogenesis is unclear, the possibility of local drug toxicity needs to be investigated. [J Pediatr Ophthalmol Strabismus. 2019;56:e28-e30.].
摘要
作者报告了1例新生儿双眼玻璃体内注射贝伐单抗后发生侵袭性早产儿视网膜病变，继而出现双眼白内障的罕见病例，且无晶状体接触的证据。虽然白内障形成的确切机制尚不清楚，但局部药物毒性的可能性需要进行研究。[《小儿眼科与斜视杂志》。2019；56：e28 - e30。]
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