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氧化锆是否有区别?全膝关节置换术后双侧后髁后稳定型假体的中期队列生存分析。

Does oxidized zirconium make a difference? Midterm cohort survivorship of symmetric posterior condyle posterior-stabilized total knee arthroplasty.

机构信息

From Kelowna Orthopedics, Kelowna, BC (Demcoe); and the Concordia Hip and Knee Institute, Division of Orthopaedic Surgery, University of Manitoba, Winnipeg, Man. (Bohm, Hedden, Burnell, Turgeon).

出版信息

Can J Surg. 2019 Apr 1;62(2):118-122. doi: 10.1503/cjs.007518.

Abstract

BACKGROUND

A novel symmetric posterior condylar design and option of a femoral component with an outer zirconium oxide layer were introduced to a successful asymmetric condylar total knee arthroplasty system in 2005. Given the paucity of information on this modified design, we performed a study to determine its early to midterm survivorship and performance.

METHODS

Patients who received the Genesis II Symmetric Posterior Condyle or Legion Primary total knee (cobalt–chromium [CoCr] or oxidized zirconium–niobium [OxZr]) (Smith & Nephew) implanted at the study centre between March 2007 and December 2013 were enrolled into a prospective database. We retrospectively reviewed the database and performed survival analysis using Kaplan–Meier techniques.

RESULTS

There were 2178 patients (1359 women [62.4%]; mean age 64.6 yr; mean body mass index 35.0) with 2815 knee replacements available for analysis. Survival rates were 98.2% (95% confidence interval [CI] 97.6%–98.7%) for failure for any reason at 2 years and 96.8% (95% CI 96.0%–97.7%) at 5 years. Age (hazard ratio [HR] 0.97, 95% CI 0.94–0.997) and female sex (HR 0.45, 95% CI 0.27–0.75) were protective, whereas body mass index (HR 1.02, 95% CI 0.99–1.05) and OxZr implant (HR 1.11, 95% CI 0.57–2.18) did not influence survivorship. Oxford Knee Score values improved from a mean of 40.2 to 21.8 by 2 years (p < 0.001), with no difference between the CoCr and OxZr groups.

CONCLUSION

The symmetric posterior condylar posterior-stabilized knee offers excellent midterm survivorship. Implant bearing surface did not have an influence on survivorship to 5 years, and, thus, use of OxZr implants may not be justified.

摘要

背景

2005 年,一种新型的对称后髁设计和一种带有外层氧化锆层的股骨组件被引入到一种成功的非对称后髁全膝关节置换系统中。鉴于这种改良设计的信息有限,我们进行了一项研究,以确定其早期至中期的存活率和性能。

方法

2007 年 3 月至 2013 年 12 月,在研究中心接受了第二代对称后髁或军团初级全膝关节(钴铬[CoCr]或氧化锆-铌[OxZr])(史赛克)植入的患者被纳入前瞻性数据库。我们回顾性地审查了数据库,并使用 Kaplan-Meier 技术进行了生存分析。

结果

共有 2178 名患者(1359 名女性[62.4%];平均年龄 64.6 岁;平均体重指数 35.0),2815 例膝关节置换术可供分析。2 年时,任何原因导致的失败的生存率为 98.2%(95%置信区间[CI]97.6%-98.7%),5 年时为 96.8%(95% CI 96.0%-97.7%)。年龄(风险比[HR]0.97,95% CI 0.94-0.997)和女性(HR 0.45,95% CI 0.27-0.75)是保护性的,而体重指数(HR 1.02,95% CI 0.99-1.05)和 OxZr 植入物(HR 1.11,95% CI 0.57-2.18)并不影响存活率。牛津膝关节评分从 2 年时的平均 40.2 分提高到 21.8 分(p<0.001),CoCr 和 OxZr 两组之间没有差异。

结论

对称后髁后稳定膝关节提供了极好的中期存活率。植入物的承载表面在 5 年内对存活率没有影响,因此使用 OxZr 植入物可能是不合理的。

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