[Histochemical localization of prostaglandin synthetase in various organs in swine and guinea pigs].

The activity of prostaglandin synthetase was studied according to the histochemical method of Janszen and Nugteren (1971), in author's own modification, in the lungs, arteries and parotid gland of the pig and in the same organs of the guinea pig. Additionally, the seminal vesicles of guinea pig were subject to investigation. A high activity of this enzyme has been found in the endothelial cells of the arteries in both species and a lower activity in the non-striated muscles of the artery wall. A high enzymatic activity has been also observed in the epithelial cells lining the bronchi and bronchioles of the lungs and in the ductus parotidicus of the parotid gland in both species, as well as in the epithelial cells of seminal vesicles in the guinea pig. A weaker, but distinct activity, has been observed in the cells of vesicles of pig parotid gland, and in the cells of stroma of guinea pig seminal vesicles.