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美国西班牙裔人群中的色素沉着障碍

Hyperpigmentation Disorders in Hispanic Population in the United States.

作者信息

Rendon Marta I.

出版信息

J Drugs Dermatol. 2019 Mar 1;18(3):s112-114.

Abstract

The Hispanic population is the third largest growing group in the United States and is projected to increase to 119 million by 2060. Skin of color populations including Hispanics are more susceptible to a variety of pigmentary disorders including melasma and post-inflammatory hyperpigmentation (PIH). Most previous treatment options for these disorders remain unsatisfactory. Current treatment options include topical therapies using skin lightening/bleaching agents, chemical peels, and physical therapies such as microdermabrasion, microneedling, radiofrequency, and lasers. Combination therapies using skin lighting agents, peels, and physical means are also commonly used. New trends include protection and prevention using sunscreens, physical blockers, and the use of new and effective anti-oxidants and anti-inflammatory agents. The choice of therapeutic agents involves assessment of the risk-benefit profile of each individual. As the pathophysiology of melasma and PIH are being intensely investigated and studied, the treatment options are also expanding. In this review, the current therapeutic options are summarized and new and emerging treatment options for PIH and melasma are discussed. J Drugs Dermatol. 2019;18(3 Suppl):s112-114.

摘要

西班牙裔人口是美国增长第三快的群体,预计到2060年将增至1.19亿。包括西班牙裔在内的有色人种皮肤更容易出现各种色素沉着紊乱,如黄褐斑和炎症后色素沉着(PIH)。此前针对这些病症的大多数治疗方案仍不尽人意。目前的治疗选择包括使用皮肤美白/脱色剂的局部疗法、化学剥脱术,以及微晶磨皮、微针、射频和激光等物理疗法。同时也常用皮肤美白剂、剥脱术和物理方法相结合的疗法。新趋势包括使用防晒霜、物理防晒剂进行防护和预防,以及使用新型有效抗氧化剂和抗炎剂。治疗药物的选择需要评估每个个体的风险效益情况。随着对黄褐斑和炎症后色素沉着病理生理学的深入研究,治疗选择也在不断扩展。在本综述中,总结了当前的治疗选择,并讨论了炎症后色素沉着和黄褐斑新出现的治疗选择。《药物皮肤病学杂志》。2019年;18(3增刊):s112 - 114。

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