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[心脏起搏器心腔内电极相关的心内膜炎。附7例报告]

[Endocarditis on cardiac pacemaker endocavitary electrodes. Apropos of 7 cases].

作者信息

Glock Y, Sabatier J, Salvador-Mazencq M, Puel P

出版信息

Arch Mal Coeur Vaiss. 1986 Apr;79(4):483-8.

PMID:3090966
Abstract

The authors report 7 cases of endocarditis on cardiac pacing catheters observed out of a total of 2 950 primary implantations and 1 600 pacemaker replacements. This is a rare condition (0.15%) but carries a poor prognosis as it usually occurs in elderly patients and demands aggressive management. The presence of multiple pacing catheters and surgical contamination due to manipulation of the pulse generator (reimplantation, pacemaker replacement) are predisposing factors. The infecting organism in these cases was a staphylococcus. One case of metastatic infection was also observed (acinetobacter). Ablation of the septic endocarditic material under effective, prolonged, double antibiotherapy is essential. Recently implanted electrodes were withdrawn by simple traction in 2 cases. This manoeuvre was attempted initially in all cases but stopped when chest pain or runs of ventricular extrasystoles occurred. Open heart explantation of pacing electrodes adherent to the ventricular apex was performed in 5 patients. Cardiopulmonary bypass without cardiac standstill enabled dissection of the fibrous rings surrounding the catheter after purging the blood from the atrial and ventricular cavities. In one patient, associated tricuspid valve endocarditis was found and valvular replacement was performed with a bioprosthesis. Endocardial pacing was replaced by epicardial pacing in patients with permanent AV block. The prognosis of this condition is poor; there were 2 deaths in this series of 7 patients.

摘要

作者报告了在总共2950例初次植入和1600例起搏器更换手术中观察到的7例心脏起搏导管心内膜炎病例。这是一种罕见疾病(0.15%),但预后较差,因为它通常发生在老年患者中,需要积极治疗。存在多条起搏导管以及因脉冲发生器操作(重新植入、起搏器更换)导致的手术污染是诱发因素。这些病例中的感染病原体为葡萄球菌。还观察到1例转移性感染(不动杆菌)。在有效的、长时间的双重抗生素治疗下切除感染性心内膜炎物质至关重要。2例近期植入的电极通过简单牵引取出。所有病例最初都尝试了这一操作,但当出现胸痛或室性早搏连发时停止。5例患者接受了附着于心尖的起搏电极的心脏直视取出术。在清除心房和心室腔中的血液后,在不使心脏停搏的情况下进行体外循环,以便分离导管周围的纤维环。1例患者发现合并三尖瓣心内膜炎,并使用生物假体进行了瓣膜置换。对于永久性房室传导阻滞患者,心内膜起搏改为心外膜起搏。这种疾病的预后较差;在这7例患者中,有2例死亡。

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