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括约肌间瘘管结扎术后患者的长期预后

Long-term outcomes in patients after ligation of the intersphincteric fistula tract.

作者信息

Osterkamp Jens, Gocht-Jensen Peter, Hougaard Kirsten, Nordentoft Tyge

出版信息

Dan Med J. 2019 Apr;66(4).

PMID:30910002
Abstract

INTRODUCTION

Ligation of the intersphincteric fistula tract (LIFT) to treat transsphincteric fistulae has yielded varied but promising results. However, it has been shown that long-term follow-up (> 250 days) is vital to obtain the correct surgical outcome. Here, we present the long-term results of patients undergoing the LIFT procedure at Herlev Hospital, Denmark.

METHODS

The study was based on a retrospective chart review of 65 consecutive patients who underwent the LIFT procedure for transsphincteric fistula-in-ano in 2011-2015.

RESULTS

At the first follow-up, at a median 50 (interquartile range (IQR): 29-92) days, there were 28 recurrences of which 17 were transsphincteric. At the long-term follow-up, a median of 274 (IQR: 162-573) days, 16 patients (ten of whom were asymptomatic at the first follow-up) presented with a recurrence, of which seven were transsphincteric; 27 patients (42%) showed complete fistula healing following their initial LIFT surgery. Another 29 patients presented complete healing after repeated surgical treatment (additional LIFT, advancement flap and/or simple incision/fistulotomy), yielding a positive outcome in 86% of our patients.

CONCLUSION

The present study shows that the LIFT procedure is a viable treatment option for transsphincteric fistulae. Furthermore, a second LIFT procedure is a plausible option for recurrent transsphincteric fistulae. In the case of recurrence, the fistula was frequently downgraded to a more benign intersphincteric variant. The study supports previous findings showing that long-term follow-up is required to successfully measure the outcome of LIFT surgery.

FUNDING

none.

TRIAL REGISTRATION

not relevant.

摘要

引言

括约肌间瘘管结扎术(LIFT)治疗经括约肌肛瘘取得了不同但颇具前景的结果。然而,研究表明长期随访(>250天)对于获得正确的手术结果至关重要。在此,我们展示丹麦赫勒夫医院接受LIFT手术患者的长期结果。

方法

本研究基于对2011年至2015年连续65例接受LIFT手术治疗经括约肌肛瘘患者的回顾性病历审查。

结果

首次随访时,中位时间为50(四分位间距(IQR):29 - 92)天,有28例复发,其中17例为经括约肌肛瘘。长期随访时,中位时间为274(IQR:162 - 573)天,16例患者(其中10例在首次随访时无症状)出现复发,其中7例为经括约肌肛瘘;27例患者(42%)在初次LIFT手术后瘘管完全愈合。另外有29例患者在重复手术治疗(额外的LIFT手术、推进皮瓣和/或简单切开/瘘管切开术)后实现完全愈合,我们的患者中有86%取得了积极结果。

结论

本研究表明LIFT手术是治疗经括约肌肛瘘的可行选择。此外,二次LIFT手术对于复发性经括约肌肛瘘是一个合理的选择。在复发的情况下,瘘管常降级为更良性的括约肌间型。该研究支持了先前的发现,即需要长期随访才能成功评估LIFT手术的结果。

资金来源

无。

试验注册

不相关。

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