阿霉素与甲氨蝶呤在子宫颈癌中的应用。一种安全有效方案的研发。
The use of Adriamycin and mehtotrexate in carcinoma of the cervix. The development of a safe effective regimen.
作者信息
Guthrie D, Way S
出版信息
Obstet Gynecol. 1978 Sep;52(3):349-54.
PMID:309102
Abstract
The results of treating 59 patients with advanced carcinoma of the cervix with Adriamycin and methotrexate are given. Five combinations of the two cytotoxic drugs have been evaluated, differing only with regard to the methotrexate. One particular regimen has been shown to be effective with a relatively high remission rate coupled with a low rate of side effects.
摘要
给出了用阿霉素和甲氨蝶呤治疗59例晚期宫颈癌患者的结果。对这两种细胞毒性药物的五种组合进行了评估，仅在甲氨蝶呤方面有所不同。已证明一种特定方案有效，缓解率相对较高且副作用发生率较低。
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