[免疫毒素疗法：抗秋水仙碱抗体对兔和小鼠急性秋水仙碱中毒的保护作用]
[Immunotoxicotherapy: protective effect of anti-colchicine antibodies in acute colchicine poisoning in rabbits and mice].
作者信息
Scherrmann J M, Terrien N, Urtizberea M, Pierson P, Bourre J M
出版信息
C R Acad Sci III. 1986;302(19):661-4.
PMID:3091202
Abstract
Anti-colchicine antibodies are able to neutralize toxic effects of colchicine after acute intoxication in rabbits and mice. The protecting effect is demonstrated by active immunization (rabbits) or passive immunization (mice). These data suggest that the immunotoxicotherapy may be useful for compounds (colchicine) with intracellular action.
摘要
抗秋水仙碱抗体能够中和兔子和小鼠急性中毒后秋水仙碱的毒性作用。主动免疫（兔子）或被动免疫（小鼠）均显示出保护作用。这些数据表明，免疫毒素疗法可能对具有细胞内作用的化合物（秋水仙碱）有用。
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