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[两种不同配制方法的肠内营养制剂细菌污染情况的临床研究]

[Clinical study of the bacterial contamination of 2 differently prepared enteral feeding solutions].

作者信息

Pfenninger E, Grünert A, John U, Wiedeck H

出版信息

Infusionsther Klin Ernahr. 1986 Jun;13(3):152-7.

PMID:3091502
Abstract

The incidence of bacterial contamination under ICU-conditions of two solutions designed for enteral feeding; the oligopeptide mixture Peptisorb and the nutrient defined diet Biosorb, were investigated. 54% of the specimens taken prior to use from the oligopeptide mixture, which is marketed as a powder and brought into solution before application, were found to be bacterially contaminated. At the end of the 6-12 h application period this percentage has risen to 79%. Prior to use the sterile packed prepared nutrient defined diet was found to be free of bacterial contamination in 97% of cases, while at the end of the period of application 21% of the samples taken contained bacteria. In most instances the solutions prepared on ICU were contaminated with gram positive spore forming bacteria and typical gram negative hospital flora. Based on the results of this investigation, only those enteral feeds which are marketed as sterile solutions should be used, in order to protect ICU patients from potential sources of contamination.

摘要

对两种用于肠内喂养的溶液在重症监护病房(ICU)条件下的细菌污染发生率进行了研究;这两种溶液分别是寡肽混合物百普素(Peptisorb)和营养成分明确的饮食产品能全力(Biosorb)。从作为粉末销售且在使用前配制成溶液的寡肽混合物中,在使用前采集的样本中有54%被发现受到细菌污染。在6至12小时的使用期结束时,这一比例升至79%。在使用前,无菌包装的预制营养成分明确的饮食产品在97%的情况下未被细菌污染,而在使用期结束时,所采集样本中有21%含有细菌。在大多数情况下,在ICU配制的溶液被革兰氏阳性芽孢形成菌和典型的革兰氏阴性医院菌群污染。基于这项调查的结果,为保护ICU患者免受潜在污染源的影响,应仅使用作为无菌溶液销售的那些肠内营养制剂。

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