Swanson A E
Int J Oral Maxillofac Surg. 1986 Aug;15(4):451-6. doi: 10.1016/s0300-9785(86)80037-0.
The clinical enigma of appropriate management of the odontogenic keratocyst is a continuing controversy. The understanding of the pathology of the lesion has undergone a significant metamorphosis over the past 30 years. Certain research findings with respect to this lesion have set it apart from the classical odontogenic cyst, while histologic and clinical observations have made its behaviour reminiscent of the ameloblastoma. Despite its benign nature, its high recurrence rate begs the question of adequacy of treatment modalities to date. Fascinating theories have been put forward to account for its apparent resistance to conventional cyst therapy. Despite this, however, there is no unanimity as to pathogenesis or correct treatment methods. The case of a large odontogenic keratocyst of the mandible is reported and a detailed narrative of its apparently successful management by relatively conservative means is documented.
牙源性角化囊肿恰当治疗的临床难题一直存在争议。在过去30年里，对该病变病理的认识发生了重大转变。关于此病变的某些研究结果使其有别于经典的牙源性囊肿，而组织学和临床观察又使其行为类似于成釉细胞瘤。尽管其本质为良性，但其高复发率让人质疑迄今为止治疗方式的充分性。人们提出了引人入胜的理论来解释其对传统囊肿治疗的明显抗性。然而，尽管如此，对于发病机制或正确的治疗方法尚无一致意见。本文报告了一例下颌骨巨大牙源性角化囊肿病例，并详细叙述了通过相对保守的方法对其进行明显成功治疗的过程。
