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Chemotherapy vs. allogeneic transplantation as post molecular remission therapy in patients aged less than 60 years with Philadelphia-positive ALL.

作者信息

Wang Libing, Du Juan, Huang Aijie, Tang Gusheng, Gong Shenglan, Cheng Hui, Zhang Weiping, Yang Jianmin, Wang Jianmin, Hu Xiaoxia

机构信息

Department of Hematology, Institute of Hematology, Changhai Hospital, 200433, Shanghai, China.

Department of Hematology, Changzheng Hospital, 200003, Shanghai, China.

出版信息

Bone Marrow Transplant. 2020 Jan;55(1):245-248. doi: 10.1038/s41409-019-0514-4. Epub 2019 Mar 27.

DOI:10.1038/s41409-019-0514-4
PMID:30918339
Abstract
摘要

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Chemotherapy vs. allogeneic transplantation as post molecular remission therapy in patients aged less than 60 years with Philadelphia-positive ALL.化疗与异基因移植作为年龄小于60岁的费城染色体阳性急性淋巴细胞白血病患者分子缓解后治疗的比较
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2
Post-remission treatment with allogeneic stem cell transplantation in patients aged 60 years and older with acute myeloid leukaemia: a time-dependent analysis.60岁及以上急性髓系白血病患者异基因干细胞移植缓解后治疗：一项时间依赖性分析
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Tyrosine kinase inhibitors improve long-term outcome of allogeneic hematopoietic stem cell transplantation for adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia.酪氨酸激酶抑制剂可改善费城染色体阳性成人急性淋巴细胞白血病患者异基因造血干细胞移植的长期疗效。
Haematologica. 2015 Mar;100(3):392-9. doi: 10.3324/haematol.2014.116954. Epub 2014 Dec 19.
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Successful treatment with imatinib-combined chemotherapy for relapsed Philadelphia-positive acute lymphoblastic leukemia after allogeneic bone marrow transplantation.伊马替尼联合化疗成功治疗异基因骨髓移植后复发的费城染色体阳性急性淋巴细胞白血病。
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Outcome of allogeneic hematopoietic stem-cell transplantation in adult patients with acute lymphoblastic leukemia: no difference in related compared with unrelated transplant in first complete remission.成年急性淋巴细胞白血病患者异基因造血干细胞移植的结果：首次完全缓解时，亲属供者移植与非亲属供者移植无差异。
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A decision analysis of allogeneic hematopoietic stem cell transplantation in adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia in first remission who have an HLA-matched sibling donor.在伴有费城染色体阴性且处于首次缓解期的 HLA 配型相合的同胞供者的成人急性淋巴细胞白血病患者中，进行异基因造血干细胞移植的决策分析。
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Cancer Med. 2024 May;13(10):e7310. doi: 10.1002/cam4.7310.
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Blood Lymphat Cancer. 2022 Mar 19;12:7-16. doi: 10.2147/BLCTT.S270134. eCollection 2022.
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Comparison of allogeneic hematopoietic stem cell transplantation and TKI combined with chemotherapy for adult philadelphia chromosome positive acute lymphoblastic leukemia: a systematic review and meta-analysis.

本文引用的文献

1
Dasatinib Plus Intensive Chemotherapy in Children, Adolescents, and Young Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Results of Children's Oncology Group Trial AALL0622.达沙替尼联合强化化疗治疗费城染色体阳性儿童、青少年和年轻成人急性淋巴细胞白血病：儿童肿瘤学组 AALL0622 试验结果。
J Clin Oncol. 2018 Aug 1;36(22):2306-2314. doi: 10.1200/JCO.2017.76.7228. Epub 2018 May 29.
2
Major molecular response prior to allogeneic hematopoietic stem cell transplantation predicts better outcome in adult Philadelphia-positive acute lymphoblastic leukemia in first remission.异基因造血干细胞移植前的主要分子反应可预测成人费城染色体阳性急性淋巴细胞白血病首次缓解期的更好预后。
Bone Marrow Transplant. 2017 Mar;52(3):470-472. doi: 10.1038/bmt.2016.307. Epub 2017 Jan 16.
3
异基因造血干细胞移植与 TKI 联合化疗治疗成人费城染色体阳性急性淋巴细胞白血病的比较：系统评价和荟萃分析。
Cancer Med. 2021 Dec;10(24):8741-8753. doi: 10.1002/cam4.4413. Epub 2021 Nov 11.
4
Is stem cell transplantation still needed for adult Philadelphia chromosome-positive acute lymphoblastic leukemia receiving tyrosine kinase inhibitors therapy?: A systematic review and meta-analysis.接受酪氨酸激酶抑制剂治疗的成人费城染色体阳性急性淋巴细胞白血病是否仍需要干细胞移植？：系统评价和荟萃分析。
PLoS One. 2021 Jun 28;16(6):e0253896. doi: 10.1371/journal.pone.0253896. eCollection 2021.
5
Evaluation and management of measurable residual disease in acute lymphoblastic leukemia.急性淋巴细胞白血病中可测量残留病的评估与管理
Ther Adv Hematol. 2020 Mar 6;11:2040620720910023. doi: 10.1177/2040620720910023. eCollection 2020.
Significance of recurrence of minimal residual disease detected by multi-parameter flow cytometry in patients with acute lymphoblastic leukemia in morphological remission.多参数流式细胞术检测急性淋巴细胞白血病形态学缓解患者微小残留病复发的意义
Am J Hematol. 2017 Mar;92(3):279-285. doi: 10.1002/ajh.24629. Epub 2017 Feb 1.
4
A sequential approach with imatinib, chemotherapy and transplant for adult Ph+ acute lymphoblastic leukemia: final results of the GIMEMA LAL 0904 study.成人Ph+急性淋巴细胞白血病采用伊马替尼、化疗和移植的序贯治疗方法：GIMEMA LAL 0904研究的最终结果
Haematologica. 2016 Dec;101(12):1544-1552. doi: 10.3324/haematol.2016.144535. Epub 2016 Aug 11.
5
Achieving Molecular Remission before Allogeneic Stem Cell Transplantation in Adult Patients with Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia: Impact on Relapse and Long-Term Outcome.在费城染色体阳性成人急性淋巴细胞白血病患者中，异基因造血干细胞移植前实现分子缓解：对复发和长期结局的影响
Biol Blood Marrow Transplant. 2016 Nov;22(11):1983-1987. doi: 10.1016/j.bbmt.2016.07.021. Epub 2016 Aug 1.
6
Impact of complete molecular response on survival in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia.完全分子反应对费城染色体阳性急性淋巴细胞白血病患者生存的影响。
Blood. 2016 Jul 28;128(4):504-7. doi: 10.1182/blood-2016-03-707562. Epub 2016 May 27.
7
Minimal residual disease-based effect and long-term outcome of first-line dasatinib combined with chemotherapy for adult Philadelphia chromosome-positive acute lymphoblastic leukemia.基于微小残留病灶的一线达沙替尼联合化疗治疗成人费城染色体阳性急性淋巴细胞白血病的疗效和长期预后。
Ann Oncol. 2016 Jun;27(6):1081-1088. doi: 10.1093/annonc/mdw123. Epub 2016 Mar 6.
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Impact of MRD and TKI on allogeneic hematopoietic cell transplantation for Ph+ALL: a study from the adult ALL WG of the JSHCT.微小残留病（MRD）和酪氨酸激酶抑制剂（TKI）对Ph+急性淋巴细胞白血病异基因造血细胞移植的影响：来自日本血液和骨髓移植学会（JSHCT）成人急性淋巴细胞白血病工作组的一项研究
Bone Marrow Transplant. 2016 Jan;51(1):43-50. doi: 10.1038/bmt.2015.217. Epub 2015 Sep 21.
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Monitoring minimal residual disease in children with high-risk relapses of acute lymphoblastic leukemia: prognostic relevance of early and late assessment.监测高危复发性急性淋巴细胞白血病患儿的微小残留病：早期和晚期评估的预后相关性。
Leukemia. 2015 Aug;29(8):1648-55. doi: 10.1038/leu.2015.59. Epub 2015 Mar 9.
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Long-term follow-up of imatinib in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia: Children's Oncology Group study AALL0031.伊马替尼治疗儿童费城染色体阳性急性淋巴细胞白血病的长期随访：儿童肿瘤学组AALL0031研究
Leukemia. 2014 Jul;28(7):1467-71. doi: 10.1038/leu.2014.30. Epub 2014 Jan 20.