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成人非 Ebstein 畸形先天性心脏病行三尖瓣手术的结果。

Results for tricuspid valve surgery in adults with congenital heart disease other than Ebstein's anomaly†.

机构信息

Department of Congenital Cardiac Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Italy.

Pediatric and Adult Congenital Cardiology, IRCCS Policlinico San Donato, San Donato Milanese, Italy.

出版信息

Eur J Cardiothorac Surg. 2019 Oct 1;56(4):706-713. doi: 10.1093/ejcts/ezz093.

Abstract

OBJECTIVES

Tricuspid valve (TV) surgery in the adult with congenital heart disease (ACHD) is a frequently performed procedure. The aim of this study was to analyse postoperative and medium-term outcomes.

METHODS

We conducted a single-centre retrospective study of patients with ACHD who underwent TV surgery (January 2000-December 2016); patients with Ebstein's anomalies were excluded. Operative and clinical records were reviewed. Outcomes considered were survival, grade of insufficiency/stenosis and TV reoperation at follow-up.

RESULTS

A total of 128 patients with ACHD had TV surgery for functional regurgitation (n = 95), dysplasia (n = 23) and systemic TV (n = 10). Median age was 40.8 years [interquartile range (IQR) 25.3]; 55.5% were men. Preoperative regurgitation was classified as mild (n = 8), moderate (n = 47) and severe (n = 70). The TV was repaired in 109 as follows: ring annuloplasty (n = 43), de Vega annuloplasty (n = 29), Wooler annuloplasty (n = 13), commissural plasty (n = 9), Kay annuloplasty (n = 7) and others (n = 8). The TV was replaced in 19 patients with biological (n = 10) and mechanical (n = 9) prostheses. The median hospital stay was 12 days (IQR 10). The overall mortality rate was 8.6% (n = 11): 2 hospital deaths (1.6%) and 9 late deaths. Survival was 93% [95% confidence interval (CI) 85-97%] at 5 years and 83% (95% CI 70-91%) at 10 years. The median follow-up period was 4.95 years (IQR 7.7) with 1 TV reoperation. Echocardiographic assessment showed ≥moderate regurgitation in 34 (34.3%) patients. Suture plasty had a significantly higher incidence of TV regurgitation ≥moderate compared to ring annuloplasty (48.9% vs 26.3%; P = 0.033).

CONCLUSIONS

TV surgery in the ACHD is frequently associated with other main procedures. Stabilizing the TV annulus with a prosthetic ring guarantees lower recurrence of moderate to severe regurgitation compared to suture plasty repair.

摘要

目的

成人先天性心脏病(ACHD)患者的三尖瓣(TV)手术是一种常见的手术。本研究旨在分析术后和中期结果。

方法

我们对 2000 年 1 月至 2016 年 12 月期间在我院接受 TV 手术的 ACHD 患者进行了单中心回顾性研究;排除了 Ebstein 异常患者。回顾了手术和临床记录。随访时考虑的结果包括存活率、功能不全/狭窄程度和 TV 再次手术。

结果

共有 128 例 ACHD 患者因功能性反流(n=95)、发育不良(n=23)和系统性 TV(n=10)接受了 TV 手术。中位年龄为 40.8 岁[四分位距(IQR)25.3];55.5%为男性。术前反流程度分为轻度(n=8)、中度(n=47)和重度(n=70)。109 例患者行 TV 修复,其中环行瓣环成形术(n=43)、De Vega 瓣环成形术(n=29)、Wooler 瓣环成形术(n=13)、瓣环成形术(n=9)、Kay 瓣环成形术(n=7)和其他(n=8)。19 例患者行生物(n=10)和机械(n=9)瓣膜置换术。中位住院时间为 12 天(IQR 10)。总体死亡率为 8.6%(n=11):2 例院内死亡(1.6%)和 9 例晚期死亡。5 年生存率为 93%[95%可信区间(CI)85-97%],10 年生存率为 83%(95% CI 70-91%)。中位随访时间为 4.95 年(IQR 7.7),有 1 例 TV 再次手术。超声心动图评估显示 34 例(34.3%)患者存在≥中度反流。与环形瓣环成形术相比,缝线成形术的 TV 反流程度≥中度的发生率明显更高(48.9% vs 26.3%;P=0.033)。

结论

成人先天性心脏病患者的三尖瓣手术常与其他主要手术同时进行。与缝线成形术修复相比,使用人工瓣环稳定 TV 瓣环可降低中重度反流的复发率。

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