Department of Dermatology, "Emek" medical center, Afula, Israel.
Department of Dermatology, Soroka medical center, Beer-Sheva, Israel.
Dermatol Ther. 2019 May;32(3):e12883. doi: 10.1111/dth.12883. Epub 2019 Apr 17.
Gram-negative bacterial toe web infection (GNBTWI) caused by Pseudomonas Aeruginosa combined with fungal infection has variety of treatments. However, these treatments have been poorly described in the literature. Our retrospective study describes patients that had been treated in our medical center with acetic acid combined with local antifungal treatment, to evaluate evidences for the appropriateness of this treatment. Ten patients with evidence of GNBTWI caused by Pseudomonas Aeruginosa combined with local fungal infection which have been treated with acetic acid in Emek Medical Center were identified. Eight patients (80%) had a complete response while two patients (20%) showed only a partial response. Side effects were minimal and included temporary stinging sensation. Acetic acid is a relatively cheap ingredient with minimal side effect profile and highly effective outcomes as a treatment for GNBTWI caused by Pseudomonas Aeruginosa and should be considered as an adjuvant treatment.
绿脓杆菌引起的趾间感染（GNBTWI）合并真菌感染的治疗方法多种多样。然而，这些治疗方法在文献中描述得很少。我们的回顾性研究描述了在我们的医疗中心接受过治疗的患者，他们使用了醋酸和局部抗真菌治疗，以评估这种治疗方法的适当性。在埃梅克医疗中心，我们发现了 10 名患有绿脓杆菌引起的 GNBTWI 合并局部真菌感染的患者，他们接受了醋酸治疗。8 名患者（80%）完全缓解，2 名患者（20%）仅部分缓解。副作用很小，包括短暂的刺痛感。醋酸是一种相对便宜的成分，副作用小，治疗绿脓杆菌引起的 GNBTWI 效果显著，应作为辅助治疗方法。
