Department of Urology, Emory University School of Medicine, Atlanta, GA; Winship Cancer Institute, Emory Healthcare, Atlanta, GA.
Department of Urology, Emory University School of Medicine, Atlanta, GA.
Urology. 2019 Jul;129:228-233. doi: 10.1016/j.urology.2019.03.015. Epub 2019 Mar 25.
To educate surgeons of distal colon urinary diversion as an alternative to ileal conduit. To assess perioperative outcomes of distal colon conduit in pelvic exenteration including conduit-related, gastrointestinal, infectious, metabolic, and wound complications within 30 days, 31-89 days, and greater than 90 days from the time of surgery.
Forty-one patients who underwent distal colon urinary diversion for malignancy, fistula, or neurogenic bladder were identified in our IRB approved database from 1/2007 to 7/2017.
Twenty-six (63.4%) were male with mean age of 54.1 years. Complications were stratified by early (≤30 days), intermediate (31-89 days), and late (≥90 days). Within 30 days, 2 (4.9%) had partial small bowel obstructions requiring nasogastric tube (NGT) placement and total parenteral nutrition (TPN); 8 (19.5%) prolonged ileus with 6 (14.6%) requiring TPN and 5 (12.2%) requiring NGT placement; 1 (2.4%) enterocutaneous fistula; 1 (2.4%) conduit hemorrhage, 10 (24.4%) treated urinary tract infections (UTIs). Between 31 and 89 days, 1 patient (2.4%) had urinary conduit leak and 3 (7.3%) treated UTIs. At ≥90 days, 2 (4.9%) had partial small bowel obstructions requiring NGT placement, 4 (9.8%) ureterocolonic strictures and 1 (2.4%) parastomal hernia, 3 (7.3%) treated UTIs. Readmission rate in ≤30 days was 10 (24.4%), 31-89 days was 13 (31.7%), and 90+ days was 16 (39%). Long-term metabolic complications at ≥90 days included 16 (39%) with hypokalemia, 10 (24.4%) with hyperchloremia, and 14 (34.1%) with metabolic acidosis.
Distal colon urinary conduit is a relatively safe and feasible option and obviates the need for small bowel anastomosis and possible associated complications.
向结肠远端尿流改道术外科医生传授该术式,作为回肠导管术的替代方案。评估骨盆切除术患者行结肠远端造口术的围手术期结果,包括术后 30 天内、31-89 天内和 90 天以上时间内与造口管相关的、胃肠道、感染、代谢和伤口并发症。
在我们的 IRB 批准的数据库中,从 2007 年 1 月至 2017 年 7 月,确定了 41 例因恶性肿瘤、瘘管或神经源性膀胱而行结肠远端尿流改道术的患者。
26 例(63.4%)为男性,平均年龄为 54.1 岁。并发症按早期(≤30 天)、中期(31-89 天)和晚期(≥90 天)分层。术后 30 天内,2 例(4.9%)发生部分小肠梗阻,需要放置鼻胃管(NGT)和全胃肠外营养(TPN);8 例(19.5%)出现迁延性肠梗阻,其中 6 例(14.6%)需要 TPN,5 例(12.2%)需要 NGT 放置;1 例(2.4%)肠外瘘;1 例(2.4%)造口管出血,10 例(24.4%)发生尿路感染(UTI)。31-89 天内,1 例(2.4%)发生尿导管漏,3 例(7.3%)发生 UTI。≥90 天内,2 例(4.9%)发生部分小肠梗阻,需要 NGT 放置,4 例(9.8%)发生输尿管结肠狭窄,1 例(2.4%)发生造口旁疝,3 例(7.3%)发生 UTI。≤30 天内的再入院率为 10 例(24.4%),31-89 天内为 13 例(31.7%),90 天以上为 16 例(39%)。≥90 天的长期代谢并发症包括 16 例(39%)低钾血症,10 例(24.4%)高氯血症和 14 例(34.1%)代谢性酸中毒。
结肠远端尿流改道术是一种相对安全可行的选择,可以避免小肠吻合术及可能相关的并发症。