Ozer Bahri, Sit Mustafa, Aktas Gulali, Keyif Fatih, Bolat Ferdi, Erkol Hayri
Department of General Surgery, Abant Izzet Baysal University Hospital, Bolu, Turkey.
Department of Internal Medicine, Abant Izzet Baysal University Hospital, Bolu, Turkey.
J Coll Physicians Surg Pak. 2019 Apr;29(4):353-355. doi: 10.29271/jcpsp.2019.04.353.
To determine the frequency of papillary thyroid micro-carcinoma (PTMC) in multinodular goiter (MNG) surgery, as well as in opposite thyroid lobule of the dominant nodule.
Descriptive study.
General Surgery Department, Abant Izzet Baysal University Hospital, between January 2010 and December 2016.
The data of 1300 patients who underwent thyroidectomy analyzed. Patients with single nodule in preoperative sonography, and patients with malignancy or suspected malignancy in fine needle aspiration cytology were excluded. PTMC was labelled as less than 10 mm in diameter.
After exclusion of such patients, 1,197 subjects with benign MNG were included in the study. There were 1,134 patients in benign group and 63 subjects in PTMC group, according to the postoperative pathology results. In PTMC group, 53 (84%) of subjects had one tumor and 10 (16%) has more than one cancerous nodules. Thirty-six (57%) of cancers in PTMC group were right sided and 27 (43%) were left sided. Cancer and dominant nodule were in the same thyroid lobe in 62% (n = 39) subjects in PTMC group. However, 24 subjects had cancer in the lobe opposite to the largest nodule.
Total bilateral thyroidectomy should be preferred in MNG surgery due to high probability of multicentric disease.
确定多结节性甲状腺肿（MNG）手术中甲状腺微小乳头状癌（PTMC）的发生率，以及优势结节对侧甲状腺叶中的发生率。
描述性研究。
2010年1月至2016年12月期间，阿班特伊泽特贝萨尔大学医院普通外科。
分析1300例行甲状腺切除术患者的数据。排除术前超声检查为单结节患者，以及细针穿刺细胞学检查为恶性或疑似恶性患者。PTMC定义为直径小于10毫米。
排除此类患者后，1197例良性MNG患者纳入研究。根据术后病理结果，良性组有1134例患者，PTMC组有63例患者。PTMC组中，53例（84%）患者有一个肿瘤，10例（16%）有多个癌结节。PTMC组中36例（57%）癌症位于右侧，27例（43%）位于左侧。PTMC组中62%（n = 39）患者的癌症与优势结节位于同一甲状腺叶。然而，24例患者的癌症位于最大结节对侧叶。
由于多中心疾病的可能性较高，MNG手术应首选双侧甲状腺全切除术。
