Ganesh Anuradha, Edmond Jane, Forbes Brian, Katowitz William R, Nischal Ken K, Miller Marilyn, Levin Alex V
Department of Ophthalmology, Sultan Qaboos University Hospital, Sultanate of Oman.
Departments of Ophthalmology and Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, Texas.
J AAPOS. 2019 Apr;23(2):66-76. doi: 10.1016/j.jaapos.2018.10.016. Epub 2019 Mar 27.
Craniosynostosis has a varied clinical spectrum, ranging from isolated single suture involvement to multisutural fusions. Syndromic and nonsyndromic patients require orchestrated and multidisciplinary care from birth to adulthood. Advances in our understanding of craniosynostosis over the last quarter-century have resulted in more systematic management of the problems associated with the syndromic and nonsyndromic forms of this condition. This review provides an update on the genetic basis of, management of strabismus and oculoplastic manifestations in, and visual surveillance of patients with craniosynostosis.
颅缝早闭具有多种临床谱系,从孤立的单条颅缝受累到多条颅缝融合。综合征型和非综合征型患者从出生到成年都需要精心安排的多学科护理。在过去四分之一世纪里,我们对颅缝早闭的认识取得了进展,这使得对与这种疾病的综合征型和非综合征型相关问题的管理更加系统化。本综述提供了关于颅缝早闭患者斜视和眼整形表现的遗传基础、管理以及视觉监测的最新情况。