美国南部接受医疗护理的 HIV 感染者中的代谢综合征：患病率和危险因素。
Metabolic Syndrome Among People Living with HIV Receiving Medical Care in Southern United States: Prevalence and Risk Factors.
机构信息
Texas Department of State Health Services, Austin, TX, USA.
TB/STD/HIV Surveillance Branch, Texas Department of State Health Services, 11501 Burnet Road, Bldg 902, Austin, TX, 78758, USA.
出版信息
AIDS Behav. 2019 Nov;23(11):2916-2925. doi: 10.1007/s10461-019-02487-8.
Using representative data among 1861 in care people living with HIV (PLWH) in four southern states (Texas, Mississippi, Florida, and Georgia) from the 2013-2014 Medical Monitoring Project (MMP) survey, we estimated the prevalence and odds of metabolic syndrome (MetS) among various demographic and HIV related risk factors. Overall MetS prevalence was 34%, with our participants being mostly black (55%), male (72%), ≥ 50 years old (46%), and overweight or obese (60%) with undetectable viral loads (≤ 200 copies/ml, 69%), and were currently taking antiretroviral medication (98%). Compared to those who were ≥ 60 years, 18-39 year olds had a 79% (95% CI 0.13-0.33) lower odds of having MetS. Women were 2.24 times more likely to have MetS than men (95% CI 1.69-2.97). Age and sex were significant predictors of MetS. Since MetS is a combination of chronic disease risk factors, regular screening for MetS risk factors among aging PLWH is crucial.
利用来自南部四个州（德克萨斯州、密西西比州、佛罗里达州和佐治亚州）的 2013-2014 年医疗监测项目（MMP）调查中 1861 名接受护理的艾滋病毒感染者（PLWH）的代表性数据，我们估计了各种人口统计学和艾滋病毒相关风险因素中代谢综合征（MetS）的流行率和几率。总体 MetS 患病率为 34%，我们的参与者主要是黑人（55%）、男性（72%）、≥50 岁（46%）、超重或肥胖（60%），病毒载量无法检测（≤200 拷贝/ml，69%），并且正在服用抗逆转录病毒药物（98%）。与≥60 岁的人相比，18-39 岁的人患 MetS 的几率低 79%（95%CI 0.13-0.33）。女性患 MetS 的可能性是男性的 2.24 倍（95%CI 1.69-2.97）。年龄和性别是 MetS 的显著预测因素。由于 MetS 是多种慢性疾病风险因素的组合，因此定期对老年 PLWH 进行 MetS 风险因素筛查至关重要。
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