Department of Cardiothoracic Surgery, Children's Hospital of Chongqing Medical University, Chongqing, China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China; Chongqing Key Laboratory of Pediatrics, Chongqing, China.
Department of Cardiothoracic Surgery, Children's Hospital of Chongqing Medical University, Chongqing, China; Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China; Chongqing Key Laboratory of Pediatrics, Chongqing, China.
Int J Infect Dis. 2019 Jun;83:102-108. doi: 10.1016/j.ijid.2019.03.032. Epub 2019 Mar 28.
The pericardial effusion (PE) caused by paragonimiasis is rarely reported. This study aims to present experience in the diagnosis and surgical management of PE due to paragonimiasis.
Medical records of 57 children who were diagnosed with PE due to paragonimiasis and underwent surgery at Children's Hospital of Chongqing Medical University between January 2012 and August 2018 were retrospectively reviewed.
The average age of this group was 7.6 ± 3.0 years. Patients were mainly from Chongqing and Sichuan areas. ELISA for Paragonimus skrjabini in all 57 patients showed positive results. Moderate or large PE were identified in 12 and 45 patients, respectively. All patients underwent surgery either by pericardectomy or thoracoscopic surgery. Pathological exams indicated massive eosinophil infiltration in all 57 specimens. After 3-4 courses of praziquantel therapy, the clinical outcomes were satisfactory.
Typical endemic history, eosinophilia and multiple serous effusion raise suspicions of paragonimiasis. Once moderate to large PE is identified in patients with paragonimiasis, surgical treatment is necessary.
由并殖吸虫引起的心包积液（PE）很少见。本研究旨在介绍并殖吸虫性 PE 的诊断和手术治疗经验。
回顾性分析 2012 年 1 月至 2018 年 8 月重庆医科大学儿童医院收治的 57 例因并殖吸虫病而行手术的儿童心包积液患者的临床资料。
该组患者的平均年龄为 7.6±3.0 岁。患者主要来自重庆和四川地区。57 例患者的 ELISA 检测对斯氏狸殖吸虫均呈阳性。12 例患者有中等量或大量心包积液，45 例患者有中等量心包积液。所有患者均行心包切除术或胸腔镜手术。57 例标本均可见大量嗜酸性粒细胞浸润。所有患者均接受 3-4 个疗程的吡喹酮治疗，临床效果满意。
典型的流行病史、嗜酸性粒细胞增多和多发性浆膜腔积液提示可能为并殖吸虫病。一旦发现并殖吸虫病患者存在中至大量心包积液，应行手术治疗。
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