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外周神经刺激对疼痛的抑制作用。植入装置的长期影响。

Pain suppression by peripheral nerve stimulation. Chronic effects of implanted devices.

作者信息

Picaza J A, Hunter S E, Cannon B W

出版信息

Appl Neurophysiol. 1977;40(2-4):223-34. doi: 10.1159/000102446.

DOI:10.1159/000102446
PMID:309314
Abstract

This is a study of the long range effects of pain suppression obtained by electrical stimulation of peripheral nerves. These cases were followed during 12--46 months and evaluated personally and by questionnaires. Selection for surgery was done exclusively on the basis of the results of a preoperative peripheral nerve stimulation test. Of 37 cases observations, 18 were considered significantly relieved; that is, more than 50% of the intensity and/or duration of pain was consistently admitted. The results obtained in the acute preoperative trial could be reproduced indefinitely in some cases for as long as 46 months. Correlation of the results with the disease producing the pain revealed as benefitting for painful syndromes associated with peripheral nerve disorders, amputation, soft tissue injuries (nerves?), and some recurrent lumbar disc surgeries. Sciatic, ulnar and occipital nerve implantations were particularly rewarding. The best and worse results were analyzed. The complications appear to be largely preventable and of no serious consequences. Our analysis suggests that most failures take place within 2 years from implantation. Experience seems to be accumulating showing that a number of patients may receive sustained relief beyond this period.

摘要

这是一项关于通过电刺激外周神经实现疼痛抑制的长期效果的研究。对这些病例进行了12至46个月的随访,并通过个人评估和问卷调查进行评价。手术选择完全基于术前外周神经刺激测试的结果。在37例观察病例中,18例被认为疼痛明显缓解;也就是说,疼痛强度和/或持续时间持续减轻超过50%。在一些病例中,术前急性试验所获得的结果在长达46个月的时间里都能无限重现。结果与引发疼痛的疾病之间的相关性显示,该方法对与外周神经疾病、截肢、软组织损伤(神经?)以及一些复发性腰椎间盘手术相关的疼痛综合征有益。坐骨神经、尺神经和枕神经植入尤其有效。分析了最佳和最差结果。并发症似乎大多可以预防,且没有严重后果。我们的分析表明,大多数失败发生在植入后的2年内。经验似乎在不断积累,表明许多患者在此之后可能会持续缓解疼痛。

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