《地梢瓜的化学成分、药理活性、毒性及临床应用》。
Phytochemistry, Pharmacological Activities, Toxicity and Clinical Application of Momordica cochinchinensis.
机构信息
Central Laboratory, Seventh People's Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China.
Institute of Interdisciplinary Medical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China.
出版信息
Curr Pharm Des. 2019;25(6):715-728. doi: 10.2174/1381612825666190329123436.
Momordica cochinchinensis (Lour.) Spreng (M. cochinchinensis) is a deciduous vine that grows in Southeast Asia. It is known as gac in Vietnam and as Red Melon in English. Gac is reputed to be extremely benificial for health and has been widely used as food and folk medicine in Southeast Asia. In China, the seed of M. cochinchinensis (Chinese name: Mu biezi) is used as traditional Chinese medicine (TCM) for the treatment of various diseases. More than 60 chemical constituents have been isolated from M. cochinchinensis. Modern pharmacological studies and clinical practice demonstrate that some chemical constituents of M. cochinchinensis possess wide pharmacological activities, such as anti-tumor, anti-oxidation, anti-inflammatory, etc. This paper reviews the phytochemistry, pharmacological activities, toxicity, and clinical application of M. cochinchinensis, aiming to bring new insights into further research and application of this ancient herb.
刺果番荔枝（Momordica cochinchinensis (Lour.) Spreng）是一种落叶藤本植物，生长在东南亚地区。在越南，它被称为“gac”，在英文中则被称为“Red Melon”。刺果番荔枝被誉为对健康极其有益的水果，在东南亚地区被广泛用作食品和民间药物。在中国，刺果番荔枝的种子（中文名称：木鳖子）被用作传统中药（TCM）来治疗各种疾病。从刺果番荔枝中已经分离出 60 多种化学成分。现代药理学研究和临床实践证明，刺果番荔枝的一些化学成分具有广泛的药理活性，如抗肿瘤、抗氧化、抗炎等。本文综述了刺果番荔枝的植物化学、药理活性、毒性和临床应用，旨在为这一古老草药的进一步研究和应用提供新的思路。
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