a Faculty of Medicine , Institut Clinic of Gynecology, Obstetrics and Neonatology, University of Barcelona, Hospital Clinic-Institut d´Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) , Barcelona , Spain.
b Department of Anesthesiology , Y.Ya. Gordeev City Clinical Hospital №1 , Saratov , Russian Federation.
Gynecol Endocrinol. 2019 Aug;35(8):651-656. doi: 10.1080/09513590.2019.1592153. Epub 2019 Apr 2.
To analyze the management of severe ovarian hyperstimulation syndrome based on aspects of its etiology and pathogenesis a systematic review of the literature was done. An evaluation of clinical trials, meta-analysis, case-reports and reviews assessing the management of different conditions related to ovarian hyperstimulation syndrome was made using the following data sources: MEDLINE Pubmed (from 1966 to July 2018) and the Cochrane Controlled Clinical Trials Register, Embase (up to July 2018). The role of intra-abdominal hypertension in the development of the severe forms of ovarian hyperstimulation syndrome and its complicated outcomes was assessed. The pathophysiology and clinic of intra-abdominal hypertension syndrome are almost identical to moderate and severe forms of ovarian hyperstimulation syndrome and associated organ dysfunction. The classic triad (respiratory disorders, reduction in venous return, and restriction of perfusion in internal organs) is present in severe ovarian hyperstimulation syndrome as well as in intra-abdominal hypertension syndrome. This review provides recommendations for the management of ovarian hyperstimulation syndrome and insight into the different medical complaints of this syndrome. The principles of therapy for intra-abdominal hypertension syndrome might be considered in the treatment of severe forms of ovarian hyperstimulation syndrome.
为了从病因和发病机制方面分析重度卵巢过度刺激综合征的管理，我们对文献进行了系统综述。利用以下数据源评估了评估与卵巢过度刺激综合征相关的不同情况管理的临床试验、荟萃分析、病例报告和综述：MEDLINE Pubmed（自 1966 年至 2018 年 7 月）和 Cochrane 对照临床试验注册中心、Embase（截至 2018 年 7 月）。评估了腹腔内高压在重度卵巢过度刺激综合征及其复杂结局发展中的作用。腹腔内高压综合征的病理生理学和临床与中重度卵巢过度刺激综合征及相关器官功能障碍几乎相同。经典三联征（呼吸障碍、静脉回流减少和内脏灌注受限）既存在于重度卵巢过度刺激综合征中，也存在于腹腔内高压综合征中。这篇综述为卵巢过度刺激综合征的管理提供了建议，并深入了解了该综合征的不同医学症状。腹腔内高压综合征的治疗原则可能被考虑用于重度卵巢过度刺激综合征的治疗。
