整脊疗法对多发性硬化症患者的影响：一项初步研究。

Effects of osteopathic manipulative treatment on patients with multiple sclerosis: A pilot study.

机构信息

IRCCS Centro Neurolesi "Bonino Pulejo", Messina, Italy.

Department of Medical and Surgical Sciences, "Magna Græcia" University of Catanzaro, Viale Europa, Germaneto, Catanzaro, Italy.

出版信息

Complement Ther Med. 2019 Apr;43:154-156. doi: 10.1016/j.ctim.2019.01.023. Epub 2019 Jan 30.

DOI:10.1016/j.ctim.2019.01.023

PMID:30935523

Abstract

OBJECTIVES

To describe the effects of osteopathic manipulative treatment in patients affected by Multiple Sclerosis (MS).

DESIGN AND SETTING

This is a pilot study involving 20 MS patients attending the IRCCS Neurolesi "Bonino-Pulejo", Messina, Italy.

INTERVENTION

The clinical evaluation was performed before starting rehabilitation treatment (T0) and after 8 weeks of treatment (T1). The CG sample undergo a conventional rehabilitation training (CRT), 5 times/week for 60 min (for a total of 40 sessions), the EG performed the same CRT (but with a different frequency, i.e. 3 times/week, for a total of 24 sessions) and a specific OMT 2 times/week for 60 min (for a total of 16 sessions).

MAIN OUTCOME MEASURES

We analyzed the scores recorded in the following main scales: Expanded Disability Status Scale (EDSS), 10 m walking test (10mWT), Hamilton anxiety rating scale (HRS-A), and the Fatigue severity scale (FSS).

RESULTS

Our data showed a reduction in the FSS score for the EG (40 ± 1,41 at T0 vs 37 ± 2,32 at T1; p = 0.04) but not in the CG (41 ± 2,41 at TO vs 39 ± 2,6 at T1) with an intergroup difference p < 0.00. An improvement of HRS-A and 10mWT was also detected in the EG.

CONCLUSIONS

Our data raise idea that OMT might be useful in rehabilitative setting in MS patients, with particular regard to anxiety and fatigue.

摘要

目的

描述整脊手法治疗多发性硬化症（MS）患者的效果。

设计和设置

这是一项涉及意大利墨西拿 IRCCS Neurolesi“Bonino-Pulejo”的 20 名 MS 患者的试点研究。

干预

临床评估在开始康复治疗（T0）前和治疗 8 周后（T1）进行。CG 组接受常规康复训练（CRT），每周 5 次，每次 60 分钟（共 40 次），EG 组进行相同的 CRT（但频率不同，即每周 3 次，共 24 次），每周 2 次进行特定的整脊手法治疗，每次 60 分钟（共 16 次）。

主要观察指标

我们分析了以下主要量表记录的分数：扩展残疾状态量表（EDSS）、10 米步行测试（10mWT）、汉密尔顿焦虑量表（HRS-A）和疲劳严重程度量表（FSS）。

结果

我们的数据显示 EG 组的 FSS 评分降低（40±1，41 在 T0 时与 37±2，32 在 T1 时；p=0.04），但 CG 组没有（41±2，41 在 TO 时与 39±2，6 在 T1 时；p<0.00），两组间存在差异（p<0.00）。EG 组的 HRS-A 和 10mWT 也有所改善。