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登革热流行期间登革热相关神经外科急症的负担:三级医疗经验

Burden of Dengue-related Neurosurgical Emergencies during an Epidemic: A Tertiary Care Experience.

作者信息

Kutty Raja Krishnan, Sreemathyamma Sunilkumar Balakrishnan, Sivanandapanicker Jyothish Laila, Mundhe Vijay, Chhabra Kapil, Peethambaran Anilkumar

机构信息

Department of Neurosurgery, Government Medical College, Thiruvananthapuram, Kerala, India.

出版信息

Asian J Neurosurg. 2019 Jan-Mar;14(1):211-218. doi: 10.4103/ajns.AJNS_318_17.

Abstract

Dengue is one of the most common flavivirus infections which can manifest from common flu-like fever to fatal hemorrhagic complication. Epidemics of dengue return every year with peaks during the rainfall claiming substantial number of lives in the tropical and subtropical regions of the world. We present manifestations of dengue in patients who underwent neurosurgery in a tertiary referral center during such an epidemic. There were total four patients referred for neurosurgical intervention as sequelae to dengue coagulopathy. Among them, three had intracranial bleeds and one had spinal cord hematoma along with intracranial hemorrhages. This small series includes the youngest reported case of dengue coagulopathy with intracranial bleed and only the second case of spontaneous intraspinal hematoma sequelae to dengue hemorrhagic fever. The situations where patients contract dengue in a setting of neurosurgical intervention are grave. The margin of safety in the presence of dengue coagulopathy is narrow. The surgeon has to outweigh benefit against risk of surgery in each individual.

摘要

登革热是最常见的黄病毒感染之一,其症状可从普通的流感样发热到致命的出血性并发症。登革热疫情每年都会出现,在降雨期间达到高峰,在世界热带和亚热带地区夺去了大量生命。我们展示了在这样一次疫情期间,在一家三级转诊中心接受神经外科手术的登革热患者的临床表现。共有4名患者因登革热凝血病后遗症被转诊进行神经外科干预。其中,3人颅内出血,1人脊髓血肿伴颅内出血。这个小系列包括报告的最年轻的登革热凝血病伴颅内出血病例,以及第二例登革热出血热自发脊髓血肿后遗症病例。在神经外科手术情况下患者感染登革热的情况很严重。存在登革热凝血病时的安全边际很窄。外科医生必须权衡每个患者手术的获益与风险。

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