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累及颅骨的促尿磷性间叶肿瘤:两例罕见病例报告

Phosphaturic Mesenchymal Tumors Involving Skull Bones: Report of Two Rare Cases.

作者信息

Mishra Toshi, Desouza Maria Alina, Patel Keyuri, Mazumdar Girish A

机构信息

Department of Histopathology, Bombay Hospital and Medical Research Centre, Mumbai, Maharashtra, India.

出版信息

Asian J Neurosurg. 2019 Jan-Mar;14(1):253-255. doi: 10.4103/ajns.AJNS_176_17.

Abstract

Phosphaturic mesenchymal tumor (PMT) is a rare tumor causing oncogenic osteomalacia (OO). Most such tumors occur in soft tissue and bones of extremities and appendicular skeleton. Intracranial location and involvement of temporal-occipital bone is extremely rare. We report two unusual cases: The first was intracranial, involving the temporal bone, while the other was a skull base tumor arising from the occipital-temporal bone. Both of them presented with paraneoplastic syndrome of OO, resembled a meningioma radiologically, and underwent gross total resection of tumor. Histologically, both of them were diagnosed as PMT, mixed connective tissue variant.

摘要

磷酸尿性间叶肿瘤(PMT)是一种导致肿瘤性骨软化症(OO)的罕见肿瘤。大多数此类肿瘤发生于四肢和附属骨骼的软组织及骨骼。颅内发生以及颞枕骨受累极为罕见。我们报告两例不寻常病例:第一例为颅内肿瘤,累及颞骨,另一例为起源于枕颞骨的颅底肿瘤。两例均表现为OO的副肿瘤综合征,影像学上类似脑膜瘤,并接受了肿瘤全切术。组织学检查显示,两例均诊断为PMT,混合型结缔组织亚型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cd1d/6417335/0fa48ea56d0e/AJNS-14-253-g001.jpg

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