Gonzalez-Compta X, Mañós-Pujol M, Foglia-Fernandez M, Peral E, Condom E, Claveguera T, Dicenta-Sousa M
Department of Oto-rhino-laryngology, Ciutat Sanitària Universitària de Bellvirge, Barcelona, Spain.
J Laryngol Otol. 1998 Apr;112(4):389-92. doi: 10.1017/s0022215100140551.
Oncogenic osteomalacia is an uncommon syndrome characterized by mineral metabolism abnormalities that disappear after the resection of an associated tumour. Head and neck is the second most frequent location of these tumours. We describe a case with an ethmoido-frontal phosphaturic mesenchymal tumour and review oncogenic osteomalacia-associated tumours. Among 21 cases found, 57 per cent affected the sinonasal area and 20 per cent the mandible. The diagnosis of the tumour lasted a mean of 4.7 years from the onset of osteomalacia, and most of them showed a significant vascular component. An aggressive surgical approach is recommended.
致癌性骨软化症是一种罕见的综合征，其特征为矿物质代谢异常，该异常在切除相关肿瘤后消失。头颈部是这些肿瘤的第二常见发病部位。我们描述了一例筛窦-额部磷尿性间叶肿瘤病例，并对致癌性骨软化症相关肿瘤进行综述。在发现的21例病例中，57%累及鼻窦区域，20%累及下颌骨。从骨软化症发病到肿瘤诊断平均持续4.7年，且大多数病例显示有显著的血管成分。建议采用积极的手术方法。
