Aulakh Roosy, Chopra Sanya
Department of Paediatrics, Government Medical College and Hospital, Chandigarh, India.
J Pediatr Neurosci. 2018 Oct-Dec;13(4):373-382. doi: 10.4103/JPN.JPN_78_18.
Childhood tuberculosis (TB) has a high incidence and prevalence in developing countries like India with tubercular meningitis (TBM) being the most common cause of death. Most cases of TBM are diagnosed late when despite adequate therapy; morbidity and mortality continue to remain high. This review aims to provide a pragmatic approach at dealing with cases of tubercular meningitis in children including clinical features, laboratory and radiological criteria, treatment options and prognostic implications. The objective of this review is to assist in early identification, proper investigation and timely treatment of TBM in children in order to reduce neurological morbidity and mortality associated with it.
在印度等发展中国家,儿童结核病发病率和患病率很高,结核性脑膜炎(TBM)是最常见的死亡原因。大多数TBM病例在诊断时已属晚期,即便接受了充分治疗,发病率和死亡率仍然居高不下。本综述旨在提供一种实用方法,用于处理儿童结核性脑膜炎病例,包括临床特征、实验室及影像学标准、治疗选择和预后影响。本综述的目的是协助早期识别、正确检查和及时治疗儿童TBM,以降低与之相关的神经疾病发病率和死亡率。