Froelich Nathan T, Rizk Elias
Neurosurgery, Penn State Hershey Medical Center, Hershey, USA.
Cureus. 2019 Jan 24;11(1):e3951. doi: 10.7759/cureus.3951.
Here, the authors present the first documented case of a patient developing central nervous system (CNS) vasculitis secondary to Langerhans cell histiocytosis (LCH) ultimately leading to stroke. LCH is a rare histiocytic disorder affecting males and females equally and typically presents in pediatric patients with a median age of 30 months. Presentation of the disease can be single-site or multisystem; and, classification of treatment is further demarcated by high risk and low risk depending on the organ systems involved. Treatment of LCH typically involves vinblastine and prednisone, as well as salvage treatment as needed.
在此，作者报告了首例有记录的因朗格汉斯细胞组织细胞增多症（LCH）继发中枢神经系统（CNS）血管炎最终导致中风的病例。LCH是一种罕见的组织细胞疾病，男女发病率相同，通常在中位年龄为30个月的儿科患者中出现。该疾病的表现可以是单部位或多系统的；并且，根据所涉及的器官系统，治疗分类进一步分为高风险和低风险。LCH的治疗通常包括长春碱和泼尼松，以及根据需要进行挽救治疗。
