前列腺癌的放射治疗。

Radiotherapy for prostate carcinoma.

作者信息

Leonard K, Stryker J A

出版信息

J Surg Oncol. 1986 Sep;33(1):1-7. doi: 10.1002/jso.2930330102.

Abstract

The charts of 96 patients who received radiotherapy at The M. S. Hershey Medical Center for their prostatic carcinoma were reviewed. The 4-year NED (no evidence of disease) survival rates for patients receiving between 6,500 and 7,000 rad of external beam radiation (EBR) were 92, 78, 56, and 50% for stages A, B, C, and D1, respectively. The 4-year NED survival rate for stage B patients was 90% for those receiving approximately 6,500 rad of EBR, 75% for those receiving approximately 7,000 rad of EBR, and 71% for those receiving interstitial implants. Bowel or urinary complications occurred in 27% (21% grade I, 3% grade II, and 3% grade III) of those receiving approximately 6,500 rad of EBR, 40% (25% grade I, 10% grade II, and 5% grade III) of those receiving 7,000 rad of EBR, and 0% of those receiving interstitial implants. The effects of stage, grade, and treatment type on NED survival and complications are discussed.

摘要

对96例在宾夕法尼亚州立大学医学院赫尔希医学中心接受前列腺癌放射治疗的患者病历进行了回顾。接受6500至7000拉德外照射（EBR）的患者，A、B、C和D1期的4年无疾病（NED）生存率分别为92%、78%、56%和50%。B期患者接受约6500拉德EBR的4年NED生存率为90%，接受约7000拉德EBR的为75%，接受间质植入的为71%。接受约6500拉德EBR的患者中，27%（I级21%，II级3%，III级3%）出现肠道或泌尿系统并发症；接受7000拉德EBR的患者中，40%（I级25%，II级10%，III级5%）出现并发症；接受间质植入的患者中无并发症发生。本文讨论了分期、分级和治疗类型对NED生存率及并发症的影响。