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下丘脑在食用蛙肾上腺组织对应激反应中的作用

Participation of hypothalamus in the response of interrenal tissue to stress of frog Rana ridibunda.

作者信息

Tureková L, Juráni M

出版信息

Endocrinol Exp. 1978 Sep;12(3):171-8.

PMID:309389
Abstract

Frogs of species Rana ridibunda were divided into 6 groups: 1. control; 2. sham operated; 3. with transsection (TS) in front of the median eminence; 4. with TS under optic chiasm; 5. with TS in front of the optic chiasm; 6. hypophysectomized. On the experimental day a half of the animals of each group was stressed by restraint and the level of plasma corticosterone was measured. The results show that TS in front of the median eminence, under optic chiasm and in front of the optic chiasm increased the resting levels of corticosterone in plasma. The most intense response to stress was observed in frogs with TS in front of the median eminence and optic chiasm, while that after TS under optic chiasm was less. Hypophysectomized frogs responded to stress by increase of corticosterone level in plasma.

摘要

泽蛙被分为6组:1. 对照组;2. 假手术组;3. 在正中隆起前方进行横切(TS);4. 在视交叉下方进行TS;5. 在视交叉前方进行TS;6. 垂体切除组。在实验当天,每组一半的动物通过束缚进行应激,然后测量血浆皮质酮水平。结果表明,在正中隆起前方、视交叉下方和视交叉前方进行TS会增加血浆中皮质酮的静息水平。在正中隆起前方和视交叉前方进行TS的青蛙对压力的反应最为强烈,而在视交叉下方进行TS后的反应则较小。垂体切除的青蛙通过血浆中皮质酮水平的升高来应对压力。

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