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低血糖血症导致糖尿病酮症酸中毒治疗中出现室性二联律和三联律:病例报告。

Ventricular bigeminy and trigeminy caused by hypophosphataemia during diabetic ketoacidosis treatment: a case report.

机构信息

Department of Pediatric Endocrinology and Diabetology, Medical University of Lublin, Lublin, Poland.

Department of Pediatric Cardiology, Medical University of Lublin, Lublin, Poland.

出版信息

Ital J Pediatr. 2019 Apr 2;45(1):42. doi: 10.1186/s13052-019-0633-y.

DOI:10.1186/s13052-019-0633-y
PMID:30940174
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6444668/
Abstract

BACKGROUND

Hypophosphatemia has many causes, and is often encountered during DKA (Diabetic Ketoacidosis) treatment. However, it rarely requires clinical intervention.

CASE PRESENTATION

Ventricular arrhythmia was observed in a 10-year-old girl with newly diagnosed type 1 diabetes mellitus and hypophosphatemia while undergoing treatment for ketoacidosis. Oral phosphate supplementation ceased ventricular arrhythmia almost completely.

CONCLUSIONS

The clinical signs of hypophosphatemia are potentially life-threatening. Therefore, physicians should be vigilant when treating patients who are at risk of hypophosphatemia. Severe hypophosphatemia accompanied by clinical symptoms requires oral or intravenous supplementation of phosphate.

摘要

背景

低磷血症有多种病因,在 DKA(糖尿病酮症酸中毒)治疗过程中经常遇到。然而,它很少需要临床干预。

病例介绍

一名 10 岁女孩被诊断为新发 1 型糖尿病伴低磷血症,在接受酮症酸中毒治疗时出现室性心律失常。口服磷酸盐补充几乎完全停止了室性心律失常。

结论

低磷血症的临床症状可能危及生命。因此,医生在治疗有低磷血症风险的患者时应保持警惕。严重低磷血症伴临床症状时需要口服或静脉补充磷酸盐。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abc6/6444668/2d5ef7f9f509/13052_2019_633_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abc6/6444668/2d5ef7f9f509/13052_2019_633_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/abc6/6444668/2d5ef7f9f509/13052_2019_633_Fig1_HTML.jpg

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2
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Pediatr Diabetes. 2018 Oct;19 Suppl 27:155-177. doi: 10.1111/pedi.12701.
3
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4
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