Cingotti M, Magnin G
Rev Fr Gynecol Obstet. 1986 Jun-Jul;81(6-7):369-72.
The inhibitory effects of cyclofenil and bromocriptine on lactation as well as FSH, prolactin and estradiol levels have been compared in control and treated females. The clinical activity of cyclofenil was lower than that of bromocriptine but was virtually free of side-effects. Cyclofenil and bromocriptine only presented similar hormonal effects at the 20th day ; this suggests that the mechanism of action of cyclofenil is more linked to secondary increases in estrogen levels than to a primary effect. Cyclofenil is of particular value in cases of vascular hypersensitivity yo ergot derivatives and for toxemic patients treated with beta-blockers.
已在对照和治疗的雌性动物中比较了环苯丙胺和溴隐亭对泌乳以及促卵泡激素、催乳素和雌二醇水平的抑制作用。环苯丙胺的临床活性低于溴隐亭，但几乎没有副作用。环苯丙胺和溴隐亭仅在第20天呈现相似的激素作用；这表明环苯丙胺的作用机制更多地与雌激素水平的继发性升高有关，而非主要作用。环苯丙胺在对麦角衍生物血管过敏的病例以及用β受体阻滞剂治疗的毒血症患者中具有特殊价值。
