Grady P A, Blaumanis O R
Stroke. 1986 Sep-Oct;17(5):946-52. doi: 10.1161/01.str.17.5.946.
Cerebral venous blood gas tensions were correlated with elevated intracranial pressure in spontaneously breathing dogs lightly anesthetized with nitrous oxide/halothane. Intracranial pressure was elevated by infusion of artificial cerebrospinal fluid into a lateral ventricle. Respiration and blood pressure were monitored. The results of these experiments indicate that cerebral venous carbon dioxide tension is increased in association with elevation in intracranial pressure. Moreover, it appears that cerebral venous pCO2 is effectively regulated at a mean of about 52 mm Hg over a wide range of intracranial pressure.
在使用氧化亚氮/氟烷进行轻度麻醉的自主呼吸犬中，脑静脉血气张力与颅内压升高相关。通过向侧脑室输注人工脑脊液来升高颅内压。监测呼吸和血压。这些实验结果表明，颅内压升高时脑静脉二氧化碳张力会增加。此外，在广泛的颅内压范围内，脑静脉pCO2似乎有效地维持在约52mmHg的平均值。
