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晶状体内透镜抽吸术在晶状体前脱位的儿科病例中的应用。

Intra-lenticular lens aspiration in paediatric cases with anterior dislocation of lens.

机构信息

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Eye (Lond). 2019 Sep;33(9):1411-1417. doi: 10.1038/s41433-019-0426-y. Epub 2019 Apr 3.

Abstract

PURPOSE

To assess the outcomes of intra-lenticular lens aspiration (ILLA) in paediatric cases with anterior dislocation of lens.

METHODS

A retrospective review of medical records of cases with anterior dislocation of the lens in children (age < 16 years) that underwent ILLA between June 2017 and May 2018 was performed. Corrected distance visual acuity (CDVA), intraocular pressure (IOP), and anterior segment findings were noted at presentation and follow-up. Surgical notes were reviewed for all cases. Post-operative central corneal thickness (CCT) and central macular thickness (CMT) were recorded.

RESULTS

Eleven eyes of eight patients with a median age of ten years underwent ILLA. There were four males and four females. The median duration of symptoms was 2 months, CDVA was 1.77 logMAR, and IOP was 16 mm of Hg. Ten eyes had corneo-lenticular touch with corneal oedema, and two had raised IOP at presentation. Homocystinuria (n = 2/8), Microspherophakia (n = 2/8), Marfan syndrome (n = 1/8), Buphthalmos (n = 1/8) and Ectopia lentis et pupillae (n = 1/8) were the identifiable causes for anterior dislocation. There were no intra-operative complications in any case. Immediate post-operative corneal oedema and raised IOP was observed in nine and three cases respectively and was treated with medical therapy. The median post-operative CDVA and IOP at 6-months was 1 logMAR and 15 mm of Hg respectively. The median CCT and CMT were 516 and 248 μm respectively. Five eyes developed a central corneal descemet scar.

CONCLUSIONS

ILLA is a safe and effective technique for surgical removal of an anteriorly dislocated lens in paediatric cases.

摘要

目的

评估晶状体内抽吸术(ILLA)治疗儿童晶状体前脱位的效果。

方法

对 2017 年 6 月至 2018 年 5 月期间接受 ILLA 治疗的儿童(年龄<16 岁)晶状体前脱位病例的病历进行回顾性分析。在就诊时和随访时记录矫正远距视力(CDVA)、眼内压(IOP)和眼前段情况。对所有病例的手术记录进行了回顾。记录术后中央角膜厚度(CCT)和中央黄斑厚度(CMT)。

结果

8 例患者的 11 只眼接受了 ILLA,中位年龄为 10 岁,其中男性 4 例,女性 4 例。中位症状持续时间为 2 个月,CDVA 为 1.77 logMAR,IOP 为 16mmHg。10 只眼存在角膜-晶状体接触伴角膜水肿,2 只眼就诊时眼压升高。同型胱氨酸尿症(n=2/8)、小晶状体(n=2/8)、马凡综合征(n=1/8)、牛眼(n=1/8)和晶状体异位伴瞳孔(n=1/8)是晶状体前脱位的可识别原因。在任何情况下都没有发生术中并发症。术后即刻有 9 只眼出现角膜水肿,3 只眼眼压升高,均采用药物治疗。6 个月时的中位术后 CDVA 和 IOP 分别为 1 logMAR 和 15mmHg。中位 CCT 和 CMT 分别为 516μm 和 248μm。5 只眼出现中央角膜后弹力层瘢痕。

结论

ILLA 是治疗儿童晶状体前脱位的一种安全有效的手术方法。

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