Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Eye (Lond). 2019 Sep;33(9):1411-1417. doi: 10.1038/s41433-019-0426-y. Epub 2019 Apr 3.
To assess the outcomes of intra-lenticular lens aspiration (ILLA) in paediatric cases with anterior dislocation of lens.
A retrospective review of medical records of cases with anterior dislocation of the lens in children (age < 16 years) that underwent ILLA between June 2017 and May 2018 was performed. Corrected distance visual acuity (CDVA), intraocular pressure (IOP), and anterior segment findings were noted at presentation and follow-up. Surgical notes were reviewed for all cases. Post-operative central corneal thickness (CCT) and central macular thickness (CMT) were recorded.
Eleven eyes of eight patients with a median age of ten years underwent ILLA. There were four males and four females. The median duration of symptoms was 2 months, CDVA was 1.77 logMAR, and IOP was 16 mm of Hg. Ten eyes had corneo-lenticular touch with corneal oedema, and two had raised IOP at presentation. Homocystinuria (n = 2/8), Microspherophakia (n = 2/8), Marfan syndrome (n = 1/8), Buphthalmos (n = 1/8) and Ectopia lentis et pupillae (n = 1/8) were the identifiable causes for anterior dislocation. There were no intra-operative complications in any case. Immediate post-operative corneal oedema and raised IOP was observed in nine and three cases respectively and was treated with medical therapy. The median post-operative CDVA and IOP at 6-months was 1 logMAR and 15 mm of Hg respectively. The median CCT and CMT were 516 and 248 μm respectively. Five eyes developed a central corneal descemet scar.
ILLA is a safe and effective technique for surgical removal of an anteriorly dislocated lens in paediatric cases.
评估晶状体内抽吸术(ILLA)治疗儿童晶状体前脱位的效果。
对 2017 年 6 月至 2018 年 5 月期间接受 ILLA 治疗的儿童(年龄<16 岁)晶状体前脱位病例的病历进行回顾性分析。在就诊时和随访时记录矫正远距视力(CDVA)、眼内压(IOP)和眼前段情况。对所有病例的手术记录进行了回顾。记录术后中央角膜厚度(CCT)和中央黄斑厚度(CMT)。
8 例患者的 11 只眼接受了 ILLA,中位年龄为 10 岁,其中男性 4 例,女性 4 例。中位症状持续时间为 2 个月,CDVA 为 1.77 logMAR,IOP 为 16mmHg。10 只眼存在角膜-晶状体接触伴角膜水肿,2 只眼就诊时眼压升高。同型胱氨酸尿症(n=2/8)、小晶状体(n=2/8)、马凡综合征(n=1/8)、牛眼(n=1/8)和晶状体异位伴瞳孔(n=1/8)是晶状体前脱位的可识别原因。在任何情况下都没有发生术中并发症。术后即刻有 9 只眼出现角膜水肿,3 只眼眼压升高,均采用药物治疗。6 个月时的中位术后 CDVA 和 IOP 分别为 1 logMAR 和 15mmHg。中位 CCT 和 CMT 分别为 516μm 和 248μm。5 只眼出现中央角膜后弹力层瘢痕。
ILLA 是治疗儿童晶状体前脱位的一种安全有效的手术方法。