Jeong Jimo, Jung Yechan, Cho YoungKown, Lee Kichang
College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, Iksan 54596, Korea.
Research Ethics Center, Office of Research Management, Korea University, Seoul 02841, Korea.
J Vet Sci. 2019 Mar;20(2):e7. doi: 10.4142/jvs.2019.20.e7. Epub 2019 Mar 8.
The magnetic resonance (MR) features of spinal epidural hemorrhage depending with the passage of time have a meaning in veterinary medicine. The aim of this study is to propose the characteristic MR image of spinal epidural hemorrhage using a lower field permanent magnet scanner in dogs. A total of 8 clinically normal beagle dogs, weighing about 9 kg, were allocated. After a baseline MR examination, spinal epidural hemorrhage was created. MR scanning was executed on days 1, 2, 3, 4, 5, 10, 15, 20, 25, and 30 using 0.25 Tesla low field MR. Transverse MR images were attained for image examination. T2W, T1W, fluid-attenuated inversion recovery (FLAIR), short tau inversion recovery (STIR), and T2-GRE sequences were used. Images were compared subjectively for signal transition assessment. Spinal epidural hemorrhage models were produced positively in 8 dogs at the T12 to L2 region. Initially, the spinal cord and epidural lesions were hyper-intense on T2W and T1W images. On T2W, FLAIR and STIR images, the spinal cord lesion was steadily hyperintense. No significant and consistent hypointense signal indicating hemorrhage was seen on T2-GRE images. This study result suggests that relatively consistent hyperinstensity on T2 and FLAIR is observed for 30 days, meanwhile T2-GRE imaging is less useful in hemorrhage detection.
脊髓硬膜外出血的磁共振(MR)特征随时间变化在兽医学中有重要意义。本研究的目的是使用低场永磁扫描仪提出犬脊髓硬膜外出血的特征性MR图像。总共分配了8只临床健康的比格犬,体重约9千克。在进行基线MR检查后,制造脊髓硬膜外出血。使用0.25特斯拉低场MR在第1、2、3、4、5、10、15、20、25和30天进行MR扫描。获取横向MR图像用于图像检查。使用T2加权(T2W)、T1加权(T1W)、液体衰减反转恢复(FLAIR)、短反转时间反转恢复(STIR)和T2梯度回波(T2-GRE)序列。主观比较图像以评估信号变化。在8只犬的T12至L2区域成功建立了脊髓硬膜外出血模型。最初,脊髓和硬膜外病变在T2W和T1W图像上呈高信号。在T2W、FLAIR和STIR图像上,脊髓病变持续呈高信号。在T2-GRE图像上未见表明出血的明显且一致的低信号。本研究结果表明,在30天内T2和FLAIR上观察到相对一致的高信号,同时T2-GRE成像在出血检测中作用较小。